Guo Zhihua, Yin Weiqiang, Wang Wei, Zhang Jianrong, Zhang Xin, Peng Guilin, Xu Xin, Huang Zhaomin, Liang Lixia, Chen Hanzhang, He Jianxing
Department of Cardiothoracic Surgery, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Guangzhou Institute of Respiratory Disease & China State Key Laboratory of Respiratory Disease, Guangzhou, China.
Eur J Cardiothorac Surg. 2016 Nov;50(5):927-932. doi: 10.1093/ejcts/ezw209. Epub 2016 Jun 14.
At present, few data exist regarding the comparisons of perioperative outcomes and recurrence of spontaneous ventilation (SV) video-assisted thoracic surgery (VATS) bullectomy using total intravenous anaesthesia (TIVA) with local anaesthesia (LA) or thoracic epidural anaesthesia (TEA). We evaluated the feasibility and safety of TIVA with LA in the management of primary spontaneous pneumothorax (PSP).
We conducted a single-institution retrospective analysis of patients undergoing VATS bullectomy between July 2011 and May 2015; 240 patients were included for analysis. Preoperative, intraoperative and postoperative variables of patients undergoing VATS bullectomy using TIVA-TEA (n = 140) were compared with those using TIVA-LA (n = 100).
Baseline demographics were similar between groups. No patients in either group required conversion to thoracotomy. Three patients (TIVA-TEA: 2; TIVA-LA: 1) required conversion to intubated general anaesthesia. Both groups had comparable surgical duration, estimated blood loss, peak EtCO and lowest intraoperative SpO level. Postoperatively, thoracic drainage volume, duration of chest tube drainage and hospitalization cost did not differ between groups. The incidence of postoperative complications between groups was not significant (2% for TIVA-TEA vs 2% for TIVA-LA, P = 1.00). Pneumothorax recurrence rate was 3% in TIVA-TEA cases (n = 4) and 2% in TIVA-LA cases (n = 2).
SV-VATS bullectomy using TIVA with LA or TEA is technically feasible and safe. Both groups have comparable short-term outcomes and recurrence rates; TIVA-LA seems a valid alternative to TIVA-TEA for the surgical management of PSP under SV.
目前,关于采用全凭静脉麻醉(TIVA)联合局部麻醉(LA)或胸段硬膜外麻醉(TEA)的自主呼吸(SV)电视辅助胸腔镜手术(VATS)肺大疱切除术的围手术期结局及复发情况的比较数据较少。我们评估了TIVA联合LA用于原发性自发性气胸(PSP)治疗的可行性和安全性。
我们对2011年7月至2015年5月期间接受VATS肺大疱切除术的患者进行了单机构回顾性分析;纳入240例患者进行分析。将采用TIVA-TEA(n = 140)的VATS肺大疱切除术患者与采用TIVA-LA(n = 100)的患者的术前、术中和术后变量进行比较。
两组间基线人口统计学特征相似。两组均无患者需要转为开胸手术。3例患者(TIVA-TEA组:2例;TIVA-LA组:1例)需要转为气管插管全身麻醉。两组的手术时间、估计失血量、呼气末二氧化碳分压峰值和术中最低血氧饱和度水平相当。术后,两组间胸腔引流量、胸管引流时间和住院费用无差异。两组间术后并发症发生率无显著差异(TIVA-TEA组为2%,TIVA-LA组为2%,P = 1.00)。TIVA-TEA组气胸复发率为3%(n = 4),TIVA-LA组为2%(n = 2)。
采用TIVA联合LA或TEA的SV-VATS肺大疱切除术在技术上是可行且安全的。两组的短期结局和复发率相当;对于SV下PSP的手术治疗,TIVA-LA似乎是TIVA-TEA的有效替代方案。