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原发性自发性气胸:双侧非插管电视胸腔镜同步治疗

Primary spontaneous pneumothorax: simultaneous treatment by bilateral non-intubated videothoracoscopy.

作者信息

Guo Zhihua, Yin Weiqiang, Zhang Xin, Xu Xin, Liu Hui, Shao Wenlong, Liu Jun, Chen Hanzhang, He Jianxing

机构信息

Department of Cardiothoracic Surgery, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China Guangzhou Institute of Respiratory Disease and China State Key Laboratory of Respiratory Disease, Guangzhou, China National Clinical Research Center for Respiratory Disease, Guangzhou, China.

Department of Anesthesiology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

出版信息

Interact Cardiovasc Thorac Surg. 2016 Aug;23(2):196-201. doi: 10.1093/icvts/ivw123. Epub 2016 May 10.

Abstract

OBJECTIVES

Through a retrospective study, we assessed the feasibility and safety of simultaneous bilateral thoracoscopic wedge resection of blebs or bullae for the treatment of primary spontaneous pneumothorax (PSP) under thoracic epidural anaesthesia with spontaneous ventilation.

METHODS

This retrospective analysis involved a cohort of 37 consecutive patients undergoing simultaneous bilateral thoracoscopic bullectomy under spontaneous ventilation thoracic epidural anaesthesia (n = 15) or intubated general anaesthesia (n = 22) between July 2011 and September 2015. The perioperative data, short-term outcomes and recurrence rates of the two groups were compared.

RESULTS

The two groups had comparable preoperative demographic profiles. There were no conversions to thoracotomy or intubated single-lung ventilation. The peak end-tidal carbon dioxide in the non-intubated group was significantly higher than that in the intubated group (mean: 48 vs 34 mmHg, P < 0.001). Both groups had comparable surgical duration, blood loss and lowest intraoperative pulse oxygen saturation level. Postoperatively, the two groups had comparable chest tube duration, volume of fluid administration, length of hospital stay and complication rates. No mortality occurred. The total anaesthesia cost in non-intubated group was significantly lower (mean: CNY 4584 vs 5649, P = 0.016). The mean follow-up was 23.6 ± 12.9 months in the non-intubated group and 21.1 ± 13.4 months in the intubated group. Two recurrent pneumothoraxes in 2 patients were observed after surgical procedures for PSP. One recurrence developed in the non-intubated group (7%) and one in the intubated group (5%).

CONCLUSIONS

Simultaneous bilateral non-intubated thoracoscopic bullectomy is not only well tolerated and technically feasible but also a safe alternative for selected patients with simultaneous bilateral PSP or with high risk of contralateral recurrence.

摘要

目的

通过一项回顾性研究,我们评估了在胸段硬膜外麻醉下自主通气时同期双侧胸腔镜肺大疱或肺气囊楔形切除术治疗原发性自发性气胸(PSP)的可行性和安全性。

方法

这项回顾性分析纳入了2011年7月至2015年9月期间连续37例行同期双侧胸腔镜肺大疱切除术的患者,其中15例在自主通气胸段硬膜外麻醉下进行,22例在气管插管全身麻醉下进行。比较两组的围手术期数据、短期结局和复发率。

结果

两组术前人口统计学特征具有可比性。均未转为开胸手术或气管插管单肺通气。非气管插管组的呼气末二氧化碳峰值显著高于气管插管组(均值:48 vs 34 mmHg,P < 0.001)。两组的手术时间、失血量和术中最低脉搏血氧饱和度水平相当。术后,两组的胸管留置时间、补液量、住院时间和并发症发生率相当。无死亡病例。非气管插管组的总麻醉费用显著更低(均值:4584元 vs 5649元,P = 0.016)。非气管插管组的平均随访时间为23.6 ± 12.9个月,气管插管组为21.1 ± 13.4个月。PSP手术后观察到2例患者出现2次复发性气胸。非气管插管组出现1例复发(7%),气管插管组出现1例复发(5%)。

结论

同期双侧非气管插管胸腔镜肺大疱切除术不仅耐受性良好且技术上可行,对于同期双侧PSP或对侧复发风险高的特定患者也是一种安全的选择。

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