Regan M P, Regan D
Department of Psychology, York University, Ontario, Canada.
Can J Neurol Sci. 1989 May;16(2):168-79. doi: 10.1017/s0317167100028845.
We describe an ultra-high resolution technique for recording evoked potentials (EPs) that are thousands of times smaller than the total EEG power. We report that two superimposed visual stimulus patterns, one modulated at F1 Hz and the other at F2 Hz, can generate 20 or more EP frequency components, each of which is contained within a bandwidth of no more than 0.004 Hz. We have developed a theoretical method for calculating the amplitudes and phases of these various cross-modulation components for different arrangements of model neurons. The relative amplitude of the various cross-modulation components seems to be a 'signature' of the particular neural model and this offers a way of testing theoretical neural models against EP data. As an illustration we compare the nonlinear EP components evoked by dichoptic stimulation with unpatterned flickering light against several models of binocular interaction. These nonlinear binocular interaction terms may offer a means of investigating binocularity in amblyopic children or infants who have low acuity in one or both eyes.
我们描述了一种超高分辨率技术，用于记录比脑电图总功率小数千倍的诱发电位（EP）。我们报告，两种叠加的视觉刺激模式，一种以F1赫兹调制，另一种以F2赫兹调制，可以产生20个或更多的EP频率成分，每个成分包含在不超过0.004赫兹的带宽内。我们已经开发出一种理论方法，用于计算不同模型神经元排列的这些各种交叉调制成分的幅度和相位。各种交叉调制成分的相对幅度似乎是特定神经模型的“特征”，这提供了一种根据EP数据测试理论神经模型的方法。作为例证，我们将双眼分视刺激与无图案闪烁光诱发的非线性EP成分与几种双眼相互作用模型进行了比较。这些非线性双眼相互作用项可能提供一种手段，用于研究一只或两只眼睛视力低下的弱视儿童或婴儿的双眼视觉。
