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心血管代谢健康指数:一种利用电子健康记录测量应激负荷的新方法。

Index of cardiometabolic health: a new method of measuring allostatic load using electronic health records.

作者信息

Nobel Lisa, Roblin Douglas W, Becker Edmund R, Druss Benjamin G, Joski Peter I, Allison Jeroan J

机构信息

a Department of Quantitative Health Sciences , University of Massachusetts Medical School , Worcester , MA , USA.

b School of Public Health , Georgia State University and Kaiser Permanente , Atlanta , GA , USA.

出版信息

Biomarkers. 2017 Jul;22(5):394-402. doi: 10.1080/1354750X.2016.1201535. Epub 2016 Jun 30.

Abstract

OBJECTIVE

We developed a measure of allostatic load from electronic medical records (EMRs), which we named "Index of Cardiometabolic Health" (ICMH).

METHODS

Data were collected from participants' EMRs and a written survey in 2005. We computed allostatic load scores using the ICMH score and two previously described approaches.

RESULTS

We included 1865 employed adults who were 25-59 years old. Although the magnitude of the association was small, all methods of were predictive of SF-12 physical component subscales (all p < 0.001).

CONCLUSION

We found that the ICMH had similar relationships with health-related quality of life as previously reported in the literature.

摘要

目的

我们从电子病历(EMR)中开发了一种应激负荷测量方法,将其命名为“心脏代谢健康指数”(ICMH)。

方法

2005年从参与者的电子病历和书面调查中收集数据。我们使用ICMH评分和两种先前描述的方法计算应激负荷分数。

结果

我们纳入了1865名年龄在25至59岁之间的在职成年人。尽管关联程度较小,但所有方法都可预测SF-12身体成分量表(所有p<0.001)。

结论

我们发现ICMH与健康相关生活质量的关系与文献中先前报道的相似。

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A systematic review of allostatic load, health, and health disparities.
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Allostatic load and health status of African Americans and whites.
Am J Health Behav. 2011 Nov;35(6):641-53. doi: 10.5993/ajhb.35.6.1.
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History of socioeconomic disadvantage and allostatic load in later life.
Soc Sci Med. 2012 Jan;74(1):75-83. doi: 10.1016/j.socscimed.2011.09.037. Epub 2011 Nov 10.
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Sex differences in age trajectories of physiological dysregulation: inflammation, metabolic syndrome, and allostatic load.
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