Dalrymple J C, Bannatyne P, Russell P, Solomon H J, Tattersall M H, Atkinson K, Carter J, Duval P, Elliott P, Friedlander M
Department of Gynaecological Oncology, King George V Memorial Hospital, Camperdown, Sydney, Australia.
Cancer. 1989 Jul 1;64(1):110-5. doi: 10.1002/1097-0142(19890701)64:1<110::aid-cncr2820640120>3.0.co;2-5.
The rate and clinical features of patients admitted to King George V Hospital with extraovarian peritoneal serous papillary carcinoma during a 9-year period were reviewed. In this time, 31 of 236 (13%) patients with an initial diagnosis of invasive serous ovarian carcinoma fulfilled the surgicopathologic criteria for this entity. All patients had disseminated tumor equivalent to ovarian Stage III and IV disease (International Federation of Gynecology and Obstetrics [FIGO]) and with predominantly high-grade neoplasms. They were managed by surgical exploration, tumor debulking where possible, and postoperative chemotherapy. A comparison with a contemporaneous series of 139 patients with primary epithelial ovarian carcinoma matched for stage and grade of disease and managed similarly showed no difference in actuarial survival. The median survival times were 11.3 months for patients with extraovarian serous papillary carcinomas and 13.5 months for patients with equivalent primary ovarian neoplasms. The features of the disease and the treatment regimens used are discussed.
回顾了在9年期间入住乔治五世国王医院的卵巢外腹膜浆液性乳头状癌患者的发病率及临床特征。在此期间，236例初步诊断为浸润性浆液性卵巢癌的患者中有31例（13%）符合该疾病的外科病理标准。所有患者均有相当于卵巢III期和IV期疾病（国际妇产科联合会[FIGO]）的播散性肿瘤，且主要为高级别肿瘤。他们接受了手术探查，尽可能进行肿瘤减灭术，并进行术后化疗。与同期139例疾病分期和分级匹配且治疗方式相似的原发性上皮性卵巢癌患者进行比较，精算生存率无差异。卵巢外浆液性乳头状癌患者的中位生存时间为11.3个月，原发性卵巢肿瘤相当的患者为13.5个月。讨论了该疾病的特征及所用的治疗方案。
