Gong Yubao, Zhao Xingyu, Wu D I, Liu Jianguo
Department of Bone and Joint Surgery, The First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China.
Department of Pathology, The First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China.
Oncol Lett. 2016 Jun;11(6):4152-4154. doi: 10.3892/ol.2016.4530. Epub 2016 May 5.
Nuchal-type fibroma, initially described in 1988 by Enzinger and Weiss, is a rare clinical entity associated with distinct subcutaneous and dermal fibrous tissue proliferation. The etiology of nuchal-type fibroma largely remains to be elucidated. Typical characteristics of this entity include hypocellular, haphazardly arranged collagen with entrapped adipose tissue, paucity of elastin and entrapped small nerves, on which the pathological diagnosis is based. Magnetic resonance imaging (MRI) is the preferred imaging modality for the detection of nuchal-type fibroma, due to its superior soft tissue resolution and multi-planar capabilities. The present study presents the unique findings of a nuchal-type fibroma arising in the shoulder of a 48-year-old man. Distinct features of the nuchal-type fibroma in the present case included hyperintensity on T1- and T2-weighted MRI. Microscopic examination revealed marked mucoid tissue degeneration. To the best of our knowledge, this is the first case report of nuchal-type fibroma presenting with these distinct features. The present findings may therefore assist with the general and differential diagnosis of nuchal-type fibroma.
项部纤维瘤最初由恩津格和魏斯于1988年描述，是一种罕见的临床实体，与皮下和真皮纤维组织的独特增生有关。项部纤维瘤的病因在很大程度上仍有待阐明。该实体的典型特征包括细胞稀少、胶原纤维排列紊乱并伴有脂肪组织包埋、弹性蛋白缺乏以及小神经包埋，病理诊断即基于这些特征。磁共振成像（MRI）因其出色的软组织分辨率和多平面成像能力，是检测项部纤维瘤的首选成像方式。本研究展示了一名48岁男性肩部出现的项部纤维瘤的独特表现。本病例中项部纤维瘤的显著特征包括在T1加权和T2加权MRI上呈高信号。显微镜检查显示有明显的黏液样组织变性。据我们所知，这是首例具有这些独特特征的项部纤维瘤病例报告。因此，本研究结果可能有助于项部纤维瘤的综合诊断和鉴别诊断。
