Hu Jia, Jin L U, He Tao, Li Yifan, Zhao Yang, Ding Y U, Li Xianxin, Liu Yunchu, Gui Yaoting, Mao Xiangming, Lai Yongqing, Ni Liangchao
Department of Urology, Peking University Shenzhen Hospital, Shenzhen, Guangdong 518036, P.R. China; Guangzhou Medical University, Guangzhou, Guangdong 510182, P.R. China; Guangdong Key Laboratory of Male Reproductive Medicine and Genetics, Peking University Shenzhen Hospital, Shenzhen PKU-HKUST Medical Center, Shenzhen, Guangdong 518036, P.R. China.
Department of Urology, Peking University Shenzhen Hospital, Shenzhen, Guangdong 518036, P.R. China; Guangdong Key Laboratory of Male Reproductive Medicine and Genetics, Peking University Shenzhen Hospital, Shenzhen PKU-HKUST Medical Center, Shenzhen, Guangdong 518036, P.R. China.
Mol Clin Oncol. 2016 Jun;4(6):1013-1016. doi: 10.3892/mco.2016.839. Epub 2016 Mar 30.
Wilms tumor or nephroblastoma is a common kidney malignant tumor in childhood, accounting for ~5% of all pediatric tumors. At present, reports on Wilms' tumor occurring in adults, particularly at ages >30 years, are extremely rare. The majority of the cases of adult Wilms' tumor are closely associated with chemotherapy. Furthermore, in rare cases, Wilms' tumor is characterized by three classic types of cells, namely blastemal, stromal and epithelial cells. We herein report a case of Wilms' tumor with three classic types of cells on histological examination in a 51 year-old male patient who had received prior chemotherapy. The patient promptly underwent radical nephrectomy and remains alive. A review of previously presented cases of adult Wilms' tumor from PubMed database was also performed.
肾母细胞瘤是儿童期常见的肾脏恶性肿瘤,约占所有儿科肿瘤的5%。目前,关于成人肾母细胞瘤的报道极为罕见,尤其是年龄大于30岁的患者。大多数成人肾母细胞瘤病例与化疗密切相关。此外,在罕见情况下,肾母细胞瘤具有三种典型细胞类型,即胚基细胞、基质细胞和上皮细胞。我们在此报告一例51岁男性患者,经组织学检查发现肾母细胞瘤具有三种典型细胞类型,该患者之前接受过化疗。患者立即接受了根治性肾切除术,目前仍然存活。我们还对PubMed数据库中之前报道的成人肾母细胞瘤病例进行了回顾。