Hsieh S P, Chen W C, Tseng H H
Department of Pathology, Veterans General Hospital-Kaohsiung, Taiwan, R.O.C.
Zhonghua Yi Xue Za Zhi (Taipei). 1996 Oct;58(4):286-90.
Wilms' tumor (nephroblastoma) is the most common intraabdominal tumor in children; its three primary components are blastemal, epithelial and stromal, with predominance of tri-phasic lesion. The tumor is rare in adults, in whom the Wilms' tumor accounts for less than 1%. The case presented here concerns a case of 46-year-old female with stage II, Wilms' tumor, composed of purely mono-phasic differentiated epithelial component with favorable histology. The patient received radical nephrectomy, than post-operative chemotherapy and radiotherapy as recommended by National Wilms' Tumor Study. With the advent of modern chemotherapy, the adult Wilms' tumor can have a better prognosis than previously. Because of the rarity of adult Wilms' tumor and its unusual histo-morphology, this case is described and the literature, reviewed.
肾母细胞瘤是儿童最常见的腹内肿瘤;其三个主要成分是胚基、上皮和间质,以三相性病变为主。该肿瘤在成人中罕见,肾母细胞瘤在成人中占比不到1%。本文介绍的病例是一名46岁女性,患有II期肾母细胞瘤,由组织学良好的纯单相分化上皮成分组成。患者接受了根治性肾切除术,然后按照国家肾母细胞瘤研究的建议进行了术后化疗和放疗。随着现代化疗的出现,成人肾母细胞瘤的预后比以前更好。由于成人肾母细胞瘤罕见且组织形态异常,故描述该病例并复习相关文献。