Binnetoglu Adem, Baglam Tekin, Tokuc Gulnur, Kecelioglu Binnetoglu Kiymet, Gerin Fatma, Sari Murat
Department of Otorhinolaryngology-Head and Neck Surgery, Marmara University Pendik Training and Research Hospital, 34899 Istanbul, Turkey.
Department of Pediatric Oncology Clinic, Marmara University Pendik Training and Research Hospital, 34899 Istanbul, Turkey.
Case Rep Otolaryngol. 2016;2016:6925234. doi: 10.1155/2016/6925234. Epub 2016 May 30.
Background. Ewing sarcoma (ES) is a high-grade malignant tumor that has skeletal and extraskeletal forms and consists of small round cells. In the head and neck region, reported localization of extraskeletal ES includes the larynx, thyroid gland, submandibular gland, nasal fossa, pharynx, skin, and parotid gland, but not the external ear canal. Methods. We present the unique case of a 2-year-old boy with extraskeletal ES arising from the external ear canal, mimicking auricular hematoma. Results. Surgery was performed and a VAC/IE (vincristine, adriamycin, cyclophosphamide alternating with ifosfamide, and etoposide) regimen was used for adjuvant chemotherapy for 12 months. Conclusion. The clinician should consider extraskeletal ES when diagnosing tumors localized in the head and neck region because it may be manifested by a nonspecific clinical picture mimicking common otorhinolaryngologic disorders.
背景。尤因肉瘤（ES）是一种高级别恶性肿瘤，有骨骼型和骨骼外型，由小圆细胞组成。在头颈部区域，报道的骨骼外ES的定位包括喉、甲状腺、下颌下腺、鼻腔、咽、皮肤和腮腺，但不包括外耳道。方法。我们报告了一例独特的病例，一名2岁男孩患有起源于外耳道的骨骼外ES，表现类似耳廓血肿。结果。进行了手术，并采用VAC/IE（长春新碱、阿霉素、环磷酰胺与异环磷酰胺和依托泊苷交替使用）方案进行辅助化疗12个月。结论。临床医生在诊断头颈部区域的肿瘤时应考虑骨骼外ES，因为它可能表现为类似常见耳鼻咽喉疾病的非特异性临床表现。
