Witas H, Bartosz G, Bryszewska M, Gwoździński K, Gondko R
Department of Biophysics, University of Lódź, Poland.
Cytobios. 1989;57(228):55-9.
Erythrocyte membrane fluidity alterations in cystic fibrosis are described. The relative flexibility of the membrane was studied using lipid spin label, i.e. methyl-5-doxylpalmitate (M5DP), and pyrene as a fluorescence probe. It was found that there was a decrease of membrane fluidity in the hydrophobic midzone of the membrane, probed by pyrene, as well as at the hydrophilic surface region, probed by M5DP.
