Fazekas F
Department of Neurology and Psychiatry, Karl Franzens University, Graz, Austria.
Eur Neurol. 1989;29(3):164-8. doi: 10.1159/000116401.
MR signal abnormalities were assessed in 87 symptom-free volunteers (31-83 years of age) and correlated with cerebrovascular risk factors, cerebral blood flow and glucose metabolism. Lesions in the subcortical and deep white matter increased from 11% in the 4th decade to 83% in subjects over 70 years of age, and were detected significantly more often in individuals with cerebrovascular risk factors (p less than 0.01). They were associated with lower slow-compartmental flow (p less than 0.05) but did not affect adjacent cortical glucose metabolism. Periventricular signal changes also increased with age but were unrelated to risk factors or functional data.
对87名无症状志愿者（年龄在31至83岁之间）的磁共振信号异常进行了评估，并将其与脑血管危险因素、脑血流量和葡萄糖代谢相关联。皮质下和深部白质病变从40岁时的11%增加到70岁以上受试者的83%，并且在有脑血管危险因素的个体中检测到的频率显著更高（p小于0.01）。它们与较低的慢室流相关（p小于0.05），但不影响相邻皮质的葡萄糖代谢。脑室周围信号变化也随年龄增加，但与危险因素或功能数据无关。
