Mari Lorenzo, Blacklock Benjamin T, Stavinohova Renata, De Risio Luisa
Neurology/Neurosurgery Service, Centre for Small Animal Studies, Animal Health Trust, Newmarket, UK.
Ophthalmology Service, Centre for Small Animal Studies, Animal Health Trust, Newmarket, UK.
Vet Ophthalmol. 2017 Sep;20(5):472-476. doi: 10.1111/vop.12396. Epub 2016 Jun 18.
A 9-month-old French Bulldog was presented with a chronic history of lateral strabismus and intermittent third eyelid protrusion in the left eye. The neuro-ophthalmological examination revealed mild ptosis of the left upper eyelid, mild lateral strabismus, and external ophthalmoparesis of the left eye. Retraction and ventral deviation of the left eye globe with protrusion of the third eyelid and elevation of the upper eyelid were elicited on attempted voluntary adduction of the left eye. Hematology, serum biochemistry, serology for infectious diseases, magnetic resonance of the head, and cerebrospinal fluid analysis did not reveal significant abnormalities. Forced duction test did not show signs of mechanical restriction in ocular motility. A suspected congenital cranial dysinnervation disorder resembling Duane retraction syndrome in humans was diagnosed based on the typical clinical signs and exclusion of structural abnormalities. The clinical signs remained stable for 9 months until the time of writing this report.
一只9个月大的法国斗牛犬因左眼慢性外斜视和间歇性第三眼睑突出就诊。神经眼科检查发现左上眼睑轻度下垂、轻度外斜视以及左眼眼外肌麻痹。试图主动内收左眼时，可引出左眼眼球后缩、向下偏斜，伴有第三眼睑突出和上眼睑抬高。血液学检查、血清生化检查、传染病血清学检查、头部磁共振成像以及脑脊液分析均未发现明显异常。被动牵拉试验未显示眼球运动存在机械性受限迹象。根据典型的临床症状并排除结构异常，诊断为疑似先天性颅神经支配障碍，类似于人类的杜安退缩综合征。直至撰写本报告时，临床症状在9个月内保持稳定。
