Department of Anesthesiology and Critical Care, Université Claude-Bernard-Lyon 1, hospices civils de Lyon, CHU de Lyon, groupe hospitalier Nord-hôpital de la Croix-Rousse, 103, grande rue de la Croix-Rousse, 69317 Lyon cedex 04, France.
Department of Anesthesiology and Critical Care, Université Claude-Bernard-Lyon 1, hospices civils de Lyon, CHU de Lyon, groupe hospitalier Nord-hôpital de la Croix-Rousse, 103, grande rue de la Croix-Rousse, 69317 Lyon cedex 04, France.
Anaesth Crit Care Pain Med. 2017 Feb;36(1):15-19. doi: 10.1016/j.accpm.2016.01.007. Epub 2016 Jun 16.
About a year after dextropropoxyphene (DXP) withdrawal from the French market, we conducted a survey among members of the French Society of Anesthesia & Intensive Care Medicine (Sfar) and of the French Society of the Study and Treatment of Pain (SFETD) to identify the indications for which this WHO level II analgesic had been prescribed, the prescriber's feedback following withdrawal, and the substitutive analgesics prescribed. DXP had been prescribed by more than 75% of the 430 anaesthesiologists and 230 pain specialists interviewed, mainly for acute and chronic non-cancer pain of moderate intensity. While two thirds of pain specialists were not satisfied with DXP withdrawal, this decision did not affect the majority of anaesthesiologists. In both groups, the main substitutive analgesic was tramadol combined with acetaminophen, while only 24% of prescribers considered acetaminophen alone as a substitute.
大约在法国市场停用右丙氧芬一年后，我们对法国麻醉与重症监护医学学会（Sfar）和法国疼痛研究与治疗学会（SFETD）的成员进行了一项调查，以确定世界卫生组织（WHO）二级镇痛药右丙氧芬的使用指征、停用后开处方者的反馈意见，以及开出处方的替代镇痛药物。接受调查的 430 名麻醉师和 230 名疼痛专家中，超过 75%的人曾开具过右丙氧芬，主要用于治疗中度急性和慢性非癌痛。尽管三分之二的疼痛专家对停用右丙氧芬不满意，但这一决定并未影响大多数麻醉师。在这两个群体中，主要的替代镇痛药物是曲马多与对乙酰氨基酚的复方制剂，而只有 24%的开处方者认为单独使用对乙酰氨基酚是一种替代药物。
