Coyne J A, Charlesworth B
Department of Ecology and Evolution, University of Chicago, Illinois 60637.
Heredity (Edinb). 1989 Feb;62 ( Pt 1):97-106. doi: 10.1038/hdy.1989.13.
Three morphological markers (yellow, miniature, and forked) are used to map the location of X-chromosome segments causing male sterility in Drosophila simulans/D. mauritiana and D. simulans/D. sechellia hybrids. In both hybridizations at least three sections of the chromosome contain genes with substantial effects on sterility. This represents the maximum genetic divergence detectable with the three markers, suggesting that the X chromosome contains many loci affecting postzygotic reproductive isolation. The tight linkage between some markers and "sterility loci" may be useful in localizing and later cloning genes important in speciation.
三种形态学标记（黄色、小型和叉状）被用于绘制在拟暗果蝇/毛里求斯果蝇以及拟暗果蝇/塞舌尔果蝇杂交种中导致雄性不育的X染色体片段的位置。在这两种杂交中，染色体的至少三个区段含有对不育有显著影响的基因。这代表了用这三种标记可检测到的最大遗传差异，表明X染色体含有许多影响合子后生殖隔离的基因座。一些标记与“不育基因座”之间的紧密连锁可能有助于定位并随后克隆在物种形成中重要的基因。
