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区域质量改进项目中阑尾切除术后结局的医院差异

Hospital variation in outcomes following appendectomy in a regional quality improvement program.

作者信息

Jenkins Peter C, Oerline Mary K, Mullard Andrew J, Englesbe Michael J, Campbell Darrell A, Hemmila Mark R

机构信息

Department of Surgery, Indiana University, North Capitol Avenue, Suite B250, Indianapolis, IN 46202, USA.

Department of Surgery, Center for Healthcare Outcomes and Policy, University of Michigan, Ann Arbor, MI, USA.

出版信息

Am J Surg. 2016 Nov;212(5):857-862. doi: 10.1016/j.amjsurg.2016.02.011. Epub 2016 May 6.

Abstract

BACKGROUND

The aim of this study was to determine hospital variation in clinical outcomes after appendectomy for acute appendicitis.

METHODS

Using data from the Michigan Surgical Quality Collaborative, we selected patients with procedure codes for open or laparoscopic appendectomy with a diagnosis of acute appendicitis (2006 to 2011). We used multivariate regression models for risk adjustment of patient-level factors and reliability adjustment for sample size differences between hospitals. Adjusted rates of outcomes for each hospital were generated by multiplying ratios of observed to expected events by overall mean event rates.

RESULTS

During the study period, 12,410 patients underwent appendectomies in 49 participating Michigan Surgical Quality Collaborative hospitals. Neither the mortality rate nor the rate of superficial or deep surgical site infection demonstrated significant variation. However, significant variation was observed for all other clinical outcomes, including a 14-fold difference of the rate of postoperative sepsis and septic shock.

CONCLUSIONS

We found significant hospital variation in outcomes after appendectomy and identified missing variables that could help to explain the observed variation. These findings have been used to enhance ongoing quality improvement efforts across the state of Michigan.

摘要

背景

本研究旨在确定急性阑尾炎阑尾切除术后临床结局的医院差异。

方法

利用密歇根外科质量协作组织的数据,我们选取了诊断为急性阑尾炎且有开放或腹腔镜阑尾切除术手术编码的患者(2006年至2011年)。我们使用多变量回归模型对患者层面因素进行风险调整,并对医院间样本量差异进行可靠性调整。通过将观察到的事件与预期事件的比率乘以总体平均事件发生率,得出每家医院的调整后结局发生率。

结果

在研究期间,密歇根外科质量协作组织的49家参与医院中有12410例患者接受了阑尾切除术。死亡率、浅表或深部手术部位感染率均未显示出显著差异。然而,所有其他临床结局均观察到显著差异,包括术后脓毒症和感染性休克发生率相差14倍。

结论

我们发现阑尾切除术后结局存在显著的医院差异,并确定了一些可能有助于解释所观察到差异的缺失变量。这些发现已被用于加强密歇根州正在进行的质量改进工作。

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