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单中心质量登记队列中5614例患者急性阑尾炎管理的趋势

Trends in the Management of Acute Appendicitis in a Single-Center Quality Register Cohort of 5,614 Patients.

作者信息

Dahlberg Martin J A, Pieniowski Emil H A, Boström Lennart Å S

机构信息

Department of Surgery, Clinical Science and Education, Stockholm South General Hospital (Södersjukhuset), Karolinska Institute, Stockholm, Sweden.

出版信息

Dig Surg. 2018;35(2):144-154. doi: 10.1159/000477269. Epub 2017 Jun 24.

DOI:10.1159/000477269
PMID:28647737
Abstract

Acute appendicitis is one of the most common reasons for emergency surgery. At Stockholm South General Hospital, information on all patients - 15 years or older - undergoing surgery for acute appendicitis is included in a quality register. Data on surgical method, preoperative imaging, hospital stay, intraoperative findings, and 30-day complications were recorded for each patient. From January 2004 to December 2014, 5,614 consecutive patients were registered. The percentage of patients examined with preoperative imaging increased from 30% in 2004 to 93% in 2014. The use of laparoscopic appendectomy increased from 6 to 79%. Negative appendectomies decreased from 7.5-10 to 1.7%. The mean perforation rate was 28.6%. Some form of postoperative complication occurred in 6.6% of those on whom laparoscopy was performed and 10.5% of those who underwent an open surgery, with a significant difference (p < 0.001) in the rate of surgical site infections (surgical site infections, higher in open cases) but with no difference in the number of deep postoperative abscesses. The overall hospital stay decreased from 2004 to 2014 for perforated and non-perforated appendicitis. The overall 30-day mortality rate was 0.12%. Changes in preoperative imaging and treatment strategy for appendicitis during this period resulted in a lower rate of negative appendectomies with acceptable complication rates and shortened hospital stay.

摘要

急性阑尾炎是急诊手术最常见的原因之一。在斯德哥尔摩南部综合医院,所有15岁及以上因急性阑尾炎接受手术的患者信息都被纳入一个质量登记册。记录了每位患者的手术方法、术前影像学检查、住院时间、术中发现以及30天并发症情况。2004年1月至2014年12月,连续登记了5614例患者。术前接受影像学检查的患者比例从2004年的30%增至2014年的93%。腹腔镜阑尾切除术的使用率从6%增至79%。阴性阑尾切除术从7.5%-10%降至1.7%。平均穿孔率为28.6%。接受腹腔镜手术的患者中有6.6%发生了某种形式的术后并发症,接受开放手术的患者中有10.5%发生了术后并发症,手术部位感染率存在显著差异(p<0.001)(开放手术病例的手术部位感染率更高),但术后深部脓肿数量无差异。2004年至2014年,穿孔性和非穿孔性阑尾炎患者的总体住院时间均有所缩短。总体30天死亡率为0.12%。这一时期阑尾炎术前影像学检查和治疗策略的改变导致阴性阑尾切除术发生率降低,并发症发生率可接受,住院时间缩短。

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