Matsuura Masato, Hirasawa Kazunori, Yanagisawa Mieko, Hirasawa Hiroyo, Murata Hiroshi, Sawamura Hiromasa, Mayama Chihiro, Asaoka Ryo
Department of Ophthalmology The University of Tokyo Graduate School of Medicine, Tokyo, Japan.
Department of Ophthalmology The University of Tokyo Graduate School of Medicine, Tokyo, Japan 2Orthoptics and Visual Science, Department of Rehabilitation, School of Allied Health Sciences, Kitasato University, Kanagawa, Japan.
Invest Ophthalmol Vis Sci. 2016 Jun 1;57(7):3276-81. doi: 10.1167/iovs.15-19024.
To investigate whether it is possible to improve estimation of the binocular visual field (VF) using monocular sensitivities on a linear scale adjusted for ocular dominance.
Monocular and binocular VF measurements were evaluated using the Humphrey Field Analyzer (HFA; 24-2 Swedish Interactive Threshold Algorithm standard program) in 60 eyes of 30 patients with open angle glaucoma. Ocular dominance was measured twice in each patient and the average value was used. Measured binocular sensitivity was then predicted based on monocular measurements using the "better sensitivity" integrated visual field (IVF) method, monocular sensitivity summation methods on the dB scale, linear scale (1/Lambert), and finally monocular sensitivity summation methods on the linear scale adjusted for the ocular dominance.
The absolute prediction error with the linear scale summation method (mean ± SD: 3.11 ± 4.00) was significantly smaller than the IVF method (3.15 ± 4.09; P = 0.014). Further, the absolute prediction error for the ocular dominance adjusted method (3.10 ± 3.99) was significantly smaller than the nonadjusted linear scale summation method (P = 0.014). The absolute prediction error associated with the dB scale summation method was significantly larger than any other method (8.15 ± 5.06; P < 0.0001).
The most accurate estimation of binocular sensitivity was achieved using the linear monocular sensitivity summation model adjusted for ocular dominance.
研究是否可以通过根据眼优势进行线性调整的单眼敏感度来改善双眼视野（VF）的估计。
使用 Humphrey 视野分析仪（HFA；24-2 瑞典交互式阈值算法标准程序）对 30 例开角型青光眼患者的 60 只眼睛进行单眼和双眼 VF 测量。每位患者测量两次眼优势，并使用平均值。然后，使用“更好的敏感度”综合视野（IVF）方法、分贝尺度上的单眼敏感度求和方法、线性尺度（1/朗伯），最后使用根据眼优势进行线性调整的单眼敏感度求和方法，基于单眼测量预测测量的双眼敏感度。
线性尺度求和方法的绝对预测误差（均值±标准差：3.11±4.00）显著小于 IVF 方法（3.15±4.09；P = 0.014）。此外，眼优势调整方法的绝对预测误差（3.10±3.99）显著小于未调整的线性尺度求和方法（P = 0.014）。与分贝尺度求和方法相关的绝对预测误差显著大于任何其他方法（8.15±5.06；P < 0.0001）。
使用根据眼优势调整的线性单眼敏感度求和模型可实现对双眼敏感度的最准确估计。
