Petersen J R, Petersen S, Serup J
Department of Neonatology, National University Hospital (Rigshospitalet)1 Department of Dermatology, Bispebjerg University Hospital2, Copenhagen, Denmark.
Skin Res Technol. 1995 May;1(2):86-9. doi: 10.1111/j.1600-0846.1995.tb00023.x.
BACKGROUND/AIMS: Skin thickness and subcutaneous fat thickness of newborn infants may reflect the condition of the infant including prematurity. Skin thickness and subcutaneous fat thickness might be useful parameters to characterize and monitor the nutritional state of the infant. The objective was to introduce ultrasonography for this purpose.
A high-frequency (20 MHz) ultrasound A-mode scanner was employed. Skinfold caliper recordings were performed for comparison. Frontal skin and skin of the back were studied in 7 infants with body weight 1095-4750 g (also studied with B-mode scanning). 46 infants weighing 925-4120 g were studied and correlated with skinfold recording.
A high degree of correlation between skinfold recordings and ultrasound measurements (A-mode) of subcutaneous fat was found, coefficient of correlation 0.84, p<0.001.
High-frequency ultrasound measurement of skin and subcutaneous fat thickness is precise and reliable for in vivo assessment of body fat in newborn infants. Further validation of the technique relative to neonatal skin and nutritional state is, however, needed before the ultrasound technique can be used as routine in neonatalogical monitoring.
背景/目的：新生儿的皮肤厚度和皮下脂肪厚度可能反映婴儿的状况，包括早产情况。皮肤厚度和皮下脂肪厚度可能是表征和监测婴儿营养状况的有用参数。目的是为此引入超声检查。
使用高频（20兆赫）超声A模式扫描仪。进行皮褶卡尺记录以作比较。对7名体重1095 - 4750克的婴儿（也进行了B模式扫描）的额部皮肤和背部皮肤进行了研究。对46名体重925 - 4120克的婴儿进行了研究，并与皮褶记录相关联。
发现皮褶记录与皮下脂肪的超声测量（A模式）之间存在高度相关性，相关系数为0.84，p<0.001。
高频超声测量皮肤和皮下脂肪厚度对于新生儿体内脂肪的评估是精确且可靠的。然而，在超声技术可用于新生儿监测的常规操作之前，还需要进一步验证该技术与新生儿皮肤和营养状况的相关性。
