Kang Yea Eun, Kim Ji Min, Choung Sorim, Joung Kyong Hye, Lee Ju Hee, Kim Hyun Jin, Ku Bon Jeong
Department of Internal Medicine, Chungnam National University School of Medicine, Daejeon 35015, Republic of Korea.
Department of Internal Medicine, Chungnam National University School of Medicine, Daejeon 35015, Republic of Korea.
Diabetes Res Clin Pract. 2016 Jul;117:1-3. doi: 10.1016/j.diabres.2016.04.007. Epub 2016 Apr 23.
We explored the role of Neuregulin 4 (Nrg4), a newly described factor secreted by adipose tissue, by measuring serum Nrg4 levels in humans. Circulating Nrg4 levels were significantly higher in patients with diabetes mellitus compared with controls without diabetes and were correlated with the serum glucose level and insulin resistance.
我们通过检测人体血清中神经调节蛋白4(Nrg4)的水平,探究了脂肪组织分泌的一种新发现因子Nrg4的作用。与非糖尿病对照组相比,糖尿病患者的循环Nrg4水平显著更高,且与血糖水平和胰岛素抵抗相关。