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终末期肾病患者的死亡率以及普通普外科手术后返回手术室的风险。

Mortality in patients with end-stage renal disease and the risk of returning to the operating room after common General Surgery procedures.

作者信息

Brakoniecki Katrina, Tam Sophia, Chung Paul, Smith Michael, Alfonso Antonio, Sugiyama Gainosuke

机构信息

Department of Surgery, SUNY Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, NY 11203, USA.

Department of Surgery, SUNY Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, NY 11203, USA; Department of Surgery, Columbia University Medical Center, New York, NY, USA.

出版信息

Am J Surg. 2017 Feb;213(2):395-398. doi: 10.1016/j.amjsurg.2016.03.009. Epub 2016 May 31.

Abstract

BACKGROUND

The prevalence of end-stage renal disease (ESRD) has increased, and there is limited data on the risks faced by this patient population undergoing surgery.

METHODS

Using American College of Surgeons National Surgical Quality Improvement Program, we identified common surgical procedures undergone by patients with ESRD. These patients were compared with a matched-control group. A subanalysis was performed to determine the risk factors for returning to the operating room in patients with ESRD.

RESULTS

Of the 195,585 patients identified, 1,163 had ESRD. ESRD was associated with increased mortality (odds ratio [OR] 9.05, confidence interval [CI] 4.09 to 20.00) and rates of return to the operating room (OR 2.97, CI 1.99 to 4.46). Returning to the OR was associated with increased operation times (98.9 vs 130.2 minutes, P < .05), mortality (OR 4.35, CI 2.11 to 8.99), and morbidity (OR 7.6, CI 4.68 to 12.41).

CONCLUSIONS

Patients with ESRD face greater risks when entering the operating room, and further study is needed to elucidate preventable risk factors.

摘要

背景

终末期肾病(ESRD)的患病率有所上升,而关于这一患者群体接受手术时所面临风险的数据有限。

方法

利用美国外科医师学会国家外科质量改进计划,我们确定了ESRD患者所接受的常见外科手术。将这些患者与匹配的对照组进行比较。进行了一项亚分析以确定ESRD患者返回手术室的危险因素。

结果

在确定的195,585例患者中,1163例患有ESRD。ESRD与死亡率增加(比值比[OR] 9.05,置信区间[CI] 4.09至20.00)和返回手术室的比率增加(OR 2.97,CI 1.99至4.46)相关。返回手术室与手术时间增加(98.9对130.2分钟,P <.05)、死亡率(OR 4.35,CI 2.11至8.99)和发病率(OR 7.6,CI 4.68至12.41)相关。

结论

ESRD患者进入手术室时面临更大风险,需要进一步研究以阐明可预防的危险因素。

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