• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

肾上腺皮质癌患者的典型库欣综合征

Classic Cushing's syndrome in a patient with adrenocortical carcinoma.

作者信息

Adkins Katelyn M, Lee James T, Bress Aaron L, Spires Susan E, Lee Cortney Y, Ayoob Andres R

出版信息

Radiol Case Rep. 2015 Nov 6;8(3):826. doi: 10.2484/rcr.v8i3.826. eCollection 2013.

DOI:10.2484/rcr.v8i3.826
PMID:27330637
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4900127/
Abstract

Adrenocortical carcinoma is an aggressive but rare neoplasm of the adrenal cortex, with an estimated incidence of approximately 2.5 per one million patients. The prognosis for patients with adrenocortical carcinoma is often very poor. Patients often present with symptoms of hormone hypersecretion but may also present with pain or a palpable mass. Imaging plays an important role in preoperative planning when clinical and biochemical findings are compatible with adrenal cortical carcinoma. We report a case of adrenocortical carcinoma in a young woman who presented with classical Cushing syndrome, but who had an atypical hormonal profile.

摘要

肾上腺皮质癌是一种侵袭性但罕见的肾上腺皮质肿瘤,估计发病率约为每百万患者2.5例。肾上腺皮质癌患者的预后通常很差。患者常表现为激素分泌过多的症状,但也可能表现为疼痛或可触及的肿块。当临床和生化检查结果与肾上腺皮质癌相符时,影像学检查在术前规划中起着重要作用。我们报告一例年轻女性肾上腺皮质癌病例,该患者表现为典型的库欣综合征,但激素谱不典型。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c439/4900127/6c8c68d6a855/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c439/4900127/9fc1c10ee3a0/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c439/4900127/a787e7247398/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c439/4900127/c0ce8984b404/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c439/4900127/0fc3981f2c38/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c439/4900127/6c8c68d6a855/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c439/4900127/9fc1c10ee3a0/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c439/4900127/a787e7247398/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c439/4900127/c0ce8984b404/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c439/4900127/0fc3981f2c38/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c439/4900127/6c8c68d6a855/gr5.jpg

相似文献

1
Classic Cushing's syndrome in a patient with adrenocortical carcinoma.肾上腺皮质癌患者的典型库欣综合征
Radiol Case Rep. 2015 Nov 6;8(3):826. doi: 10.2484/rcr.v8i3.826. eCollection 2013.
2
Cleveland Clinic experience with adrenal Cushing's syndrome.克利夫兰诊所治疗肾上腺皮质醇增多症的经验。
J Urol. 1997 Dec;158(6):2051-5; quiz 2275. doi: 10.1016/s0022-5347(01)68151-5.
3
PRKAR1A-negative familial Cushing's syndrome: two case reports.PRKAR1A基因阴性的家族性库欣综合征:两例病例报告
J Med Case Rep. 2015 Dec 1;9:277. doi: 10.1186/s13256-015-0757-7.
4
[ACTH secretion and adrenocortical responsiveness in Cushing's syndrome due to adrenocortical hyperplasia (author's transl)].肾上腺皮质增生所致库欣综合征的促肾上腺皮质激素分泌及肾上腺皮质反应性(作者译)
Nihon Naibunpi Gakkai Zasshi. 1976 Aug 20;52(8):828-44. doi: 10.1507/endocrine1927.52.8_828.
5
An Interesting Case of Hepatic Adrenocortical Carcinoma.肝肾上腺皮质癌的一个有趣病例
Acta Med Indones. 2018 Jul;50(3):257-259.
6
Cushing's syndrome: analysis of 188 cases.库欣综合征:188例病例分析。
Taiwan Yi Xue Hui Za Zhi. 1989 Sep;88(9):886-93.
7
Surgical management of Cushing's syndrome with emphasis on adrenal autotransplantation.库欣综合征的外科治疗,重点是肾上腺自体移植。
Ann Surg. 1978 Sep;188(3):290-307. doi: 10.1097/00000658-197809000-00004.
8
[Adrenocortical carcinoma].
Harefuah. 2008 Jun;147(6):520-5, 574.
9
ONCOCYTIC ADRENOCORTICAL CARCINOMA IN A YOUNG PATIENT.一名年轻患者的嗜酸细胞性肾上腺皮质癌
Acta Endocrinol (Buchar). 2022 Jul-Sep;18(3):383-386. doi: 10.4183/aeb.2022.383.
10
Tumors of the adrenal cortex and Cushing's syndrome.
Ann Surg. 1985 May;201(5):586-94. doi: 10.1097/00000658-198505000-00007.

引用本文的文献

1
Osilodrostat Treatment for Adrenal and Ectopic Cushing Syndrome: Integration of Clinical Studies With Case Presentations.奥西卓司他治疗肾上腺性和异位库欣综合征:临床研究与病例报告的整合
J Endocr Soc. 2025 Feb 14;9(4):bvaf027. doi: 10.1210/jendso/bvaf027. eCollection 2025 Mar 3.

本文引用的文献

1
Discerning malignancy in resected adrenocotical tumors.鉴别切除的肾上腺皮质肿瘤中的恶性肿瘤
Expert Opin Med Diagn. 2008 Oct;2(10):1095-105. doi: 10.1517/17530059.2.10.1095.
2
Rosiglitazone inhibits adrenocortical cancer cell proliferation by interfering with the IGF-IR intracellular signaling.罗格列酮通过干扰胰岛素样生长因子-1受体(IGF-IR)细胞内信号传导来抑制肾上腺皮质癌细胞增殖。
PPAR Res. 2008;2008:904041. doi: 10.1155/2008/904041. Epub 2008 Jul 28.
3
Adrenocortical carcinoma: contrast washout characteristics on CT.肾上腺皮质癌:CT上的对比剂洗脱特征
AJR Am J Roentgenol. 2006 Jul;187(1):W21-4. doi: 10.2214/AJR.04.1751.
4
Clinical review: Adrenocortical carcinoma: clinical update.临床综述:肾上腺皮质癌:临床进展
J Clin Endocrinol Metab. 2006 Jun;91(6):2027-37. doi: 10.1210/jc.2005-2639. Epub 2006 Mar 21.
5
Value of chemical shift subtraction MRI in characterization of adrenal masses.化学位移减法磁共振成像在肾上腺肿块特征性诊断中的价值
AJR Am J Roentgenol. 2006 Jan;186(1):130-5. doi: 10.2214/AJR.04.1370.
6
Mitotane for adrenocortical carcinoma treatment.米托坦用于肾上腺皮质癌的治疗。
Curr Opin Investig Drugs. 2005 Apr;6(4):386-94.
7
Adrenocortical carcinomas and adrenal pheochromocytomas: mass and enhancement loss evaluation at delayed contrast-enhanced CT.肾上腺皮质癌和肾上腺嗜铬细胞瘤:延迟增强CT对肿块及强化减退的评估
Radiology. 2005 Feb;234(2):479-85. doi: 10.1148/radiol.2342031876.
8
NIH state-of-the-science statement on management of the clinically inapparent adrenal mass ("incidentaloma").美国国立卫生研究院关于临床无症状肾上腺肿块(“偶发瘤”)管理的科学现状声明。
NIH Consens State Sci Statements. 2002;19(2):1-25.
9
Adrenal cortical carcinoma.肾上腺皮质癌
World J Surg. 2001 Jul;25(7):914-26. doi: 10.1007/s00268-001-0030-7.
10
Characterization of indeterminate (lipid-poor) adrenal masses: use of washout characteristics at contrast-enhanced CT.不确定(脂质含量低)肾上腺肿块的特征:在对比增强CT上利用洗脱特征
Radiology. 2000 Dec;217(3):798-802. doi: 10.1148/radiology.217.3.r00dc29798.