Khalighi Hamid Reza, Mortazavi Hamed, Mojahedi Seyed Masoud, Azari-Marhabi Saranaz, Moradi Abbasabadi Faranak
Department of Oral and Maxillofacial Medicine, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Laser, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran,Iran.
J Lasers Med Sci. 2016 Winter;7(1):45-50. doi: 10.15171/jlms.2016.10. Epub 2016 Jan 7.
Temporomandibular disorders (TMD) lead to masticatory muscle pain, jaw movement disability and limitation in mouth opening. Pain is the chief complaint in 90% of the TMD patients which leads to disability and severe socioeconomic costs. The purpose of this study was to evaluate the therapeutic effects of low level laser therapy (LLLT) compared to pharmacotherapy with NSAIDs (naproxen) in myofascial pain disorder syndrome (MPDS).
In this randomized controlled clinical trial, 40 MPDS patients were divided into two groups. One group received naproxen 500 mg bid for 3 weeks as treatment modality and also had placebo laser sessions. The other group received active laser (diode 810 nm CW) as treatment and placebo drug. Pain intensity was measured by visual analogue scale (VAS) and maximum painless mouth opening was also measured as a functional index every session and at 2 months follow up. Data was collected and analyzed with SPSS software. Independent t test was used to analyze the data. A P < 0.05 was considered significant.
Low level laser caused significant reduction in pain intensity (P < 0.05) and a significant increase in mouth opening. In naproxen group neither pain intensity nor maximum mouth opening had significant improvement. Pain relief, in subjective VAS was observed in third session in LLLT group, but did not occur in naproxen group. Maximum mouth opening increased significantly in laser group compared to the naproxen group from the eighth session.
Treatment with LLLT caused a significant improvement in mouth opening and pain intensity in patients with MPDS. Similar improvement was not observed in naproxen group.
颞下颌关节紊乱病(TMD)会导致咀嚼肌疼痛、下颌运动障碍以及张口受限。疼痛是90%的TMD患者的主要诉求,这会导致功能障碍并产生高昂的社会经济成本。本研究的目的是评估低强度激光疗法(LLLT)与非甾体抗炎药(萘普生)药物治疗相比,在肌筋膜疼痛障碍综合征(MPDS)中的治疗效果。
在这项随机对照临床试验中,40名MPDS患者被分为两组。一组接受萘普生500毫克,每日两次,共3周作为治疗方式,同时接受安慰剂激光治疗。另一组接受活性激光(810纳米连续波二极管激光)治疗并服用安慰剂药物。通过视觉模拟量表(VAS)测量疼痛强度,每次治疗时以及随访2个月时还测量最大无痛张口度作为功能指标。使用SPSS软件收集和分析数据。采用独立t检验分析数据。P < 0.05被认为具有统计学意义。
低强度激光治疗使疼痛强度显著降低(P < 0.05),张口度显著增加。在萘普生组,疼痛强度和最大张口度均未得到显著改善。在低强度激光治疗组,主观VAS评分在第三次治疗时观察到疼痛缓解,但萘普生组未出现。与萘普生组相比,激光治疗组从第八次治疗开始最大张口度显著增加。
低强度激光治疗使MPDS患者的张口度和疼痛强度得到显著改善。萘普生组未观察到类似的改善。