Chiniforush Nasim, Pourhajibagher Maryam, Shahabi Sima, Kosarieh Emad, Bahador Abbas
Laser Research Center of Dentistry, Dental Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Department of Microbiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
J Lasers Med Sci. 2016 Spring;7(2):76-85. doi: 10.15171/jlms.2016.14. Epub 2016 Mar 27.
In order to achieve a long-lasting effect, one of the main goals in root canal treatment is to eliminate the endodontic bacteria. Conventional chemomechanical debridement is considered as the basic treatment in root canal therapy, but adjunctive techniques such as antimicrobial photodynamic therapy (aPDT) can also be helpful. The aim of this study was to evaluate reports in the scientific literature that used different photosensitizers (PSs) for bacterial reduction. The literature search was conducted using databases including PubMed, Scopus, and Google Scholar with the keywords "photodynamic therapy," "antimicrobial photodynamic therapy," or "photoactivated disinfection" and "endodontic," "Enterococcus faecalis," or "root canal treatment," from 2000 to 2015. By evaluating different studies, it was concluded that aPDT should be applied in combination with conventional mechanical debridement and irrigants. However, it is also important to note that the success rate is critically dependent on the type of the PS, output power of the laser used, irradiation time, pre-irradiation time, and type of tips used.
为了获得持久的效果，根管治疗的主要目标之一是消除牙髓细菌。传统的化学机械清创术被认为是根管治疗的基本方法，但辅助技术如抗菌光动力疗法（aPDT）也可能有所帮助。本研究的目的是评估科学文献中使用不同光敏剂（PSs）减少细菌的报告。使用包括PubMed、Scopus和谷歌学术在内的数据库进行文献检索，关键词为“光动力疗法”、“抗菌光动力疗法”或“光活化消毒”以及“牙髓病学”、“粪肠球菌”或“根管治疗”，检索时间为2000年至2015年。通过评估不同的研究得出结论，aPDT应与传统的机械清创术和冲洗液联合应用。然而，同样重要的是要注意，成功率严重依赖于PS的类型、所用激光的输出功率、照射时间、照射前时间以及所用尖端的类型。
