Watanabe Isao, Nakayama Takahisa, Yamada Eiji, Tsukino Mitsuhiro, Hayashi Eiichi
Department of Respiratory Diseases, Hikone Municipal Hospital, 1882 Hassaka-cho, Hikone, Shiga, Hikone 522-8539, Japan.
Laboratory of Diagnostic Pathology, Hikone Municipal Hospital, 1882 Hassaka-cho, Hikone, Shiga, Hikone 522-8539, Japan.
Med Mycol Case Rep. 2014 Dec 19;7:15-9. doi: 10.1016/j.mmcr.2014.12.001. eCollection 2015 Mar.
A patient with pulmonary bullae died of massive hemoptysis. At autopsy a hole was observed in the aortic wall. A microscopic examination indicated small Aspergillus lesions in pulmonary bullae and extensive necrotic lesions with Aspergillus hyphae in the media of the thoracic aorta. These findings led to a diagnosis of invasive aspergillosis in the aortic arch. This is a rare case in which Aspergillus invaded the aorta in a patient without hematologic neoplasms or neutropenia.
一名患有肺大疱的患者死于大量咯血。尸检时发现主动脉壁有一个洞。显微镜检查显示肺大疱中有小的曲霉菌病变,胸主动脉中膜有广泛的坏死病变并伴有曲霉菌菌丝。这些发现导致诊断为主动脉弓侵袭性曲霉菌病。这是一例罕见的病例,曲霉菌侵袭了一名没有血液系统肿瘤或中性粒细胞减少症的患者的主动脉。