Centre for Infectious Diseases and Microbiology, Westmead Hospital, Westmead, New South Wales, Australia.
J Clin Microbiol. 2011 May;49(5):2067-71. doi: 10.1128/JCM.02615-10. Epub 2011 Mar 23.
Angioinvasive complications of Scedosporium infections are rare. We report two cases of mycotic aneurysm, following apparent localized infection, due to Scedosporium apiospermum and Pseudallescheria boydii. The thoracoabdominal aorta was affected in one patient, and cerebral vessels were affected in the other. Despite voriconazole therapy and surgical resection, the patients died. Previously reported cases are reviewed.
棘白菌素类真菌感染引起的血行播散性并发症较为罕见。我们报告两例真菌性动脉瘤,均由枝顶孢霉和拟青霉引起,表现为局部感染后明显播散。1 例累及胸主动脉和腹主动脉,另 1 例累及脑动脉。尽管给予伏立康唑治疗和手术切除,患者最终死亡。我们对既往报道的病例进行了回顾。