Ohtake T, Watanabe T, Kosaka N, Momose T, Nishikawa J, Iio M, Kawakubo K, Toda I, Sugimoto T
Kaku Igaku. 1989 Feb;26(2):195-212.
To assess the cardiac response to various exercise in ischemic heart disease (IHD), left ventricular function was continuously measured with an ambulatory ventricular monitor (VEST) in 3 normal subjects and 15 IHD patients. Treadmill exercise (early stage (E1), end stage (E2) and recovery standing state (RE], walking (WK) and climbing stairs (CS), was used for exercise. 15 IHD patients were divided into 4 groups by the LVEF response to treadmill exercise. In group 1 (G1), LVEF increased gradually at stage 1 and became plateau from stage 2 to end stage like normal group. In group 2 (G2), LVEF increased at stage 1 and became plateau from stage 2 but decreased from maximal EF more than 5% at end stage. In group 3 (G3), LVEF increased only at stage 1 and decreased immediately after stage 1 to end stage. The decrease of LVEF at end stage from standing was more than 5%. In group 4 (G4), LVEF decreased at stage 1 and became minimum at end stage. This grouping was well related to thallium redistribution (Tl RD) score and coronary arteriography (CAG) score. We could predict the severity of coronary artery disease from this grouping because all group 3 or 4 patients had severe coronary artery disease. VEST was useful for the evaluation for the tolerance to daily activities. Group 1, 2 and 3 tolerated daily activities while group 4 could not always. The degree of the increase in cardiac output during ischemia evaluated by VEST may be one of the useful index of the tolerance to exercise. In conclusion VEST was very useful for evaluating cardiac capacity of ischemic heart disease patients during various exercise.
为评估缺血性心脏病(IHD)患者对各种运动的心脏反应,使用动态心室监测仪(VEST)对3名正常受试者和15名IHD患者的左心室功能进行连续测量。运动方式包括跑步机运动(早期(E1)、末期(E2)和恢复站立状态(RE))、步行(WK)和爬楼梯(CS)。15名IHD患者根据跑步机运动时左室射血分数(LVEF)的反应分为4组。第1组(G1),LVEF在第1阶段逐渐增加,从第2阶段到末期像正常组一样达到平台期。第2组(G2),LVEF在第1阶段增加,从第2阶段开始达到平台期,但在末期从最大EF值下降超过5%。第3组(G3),LVEF仅在第1阶段增加,在第1阶段后立即下降至末期。从站立状态到末期LVEF的下降超过5%。第4组(G4),LVEF在第1阶段下降,在末期降至最低。这种分组与铊再分布(Tl RD)评分和冠状动脉造影(CAG)评分密切相关。我们可以根据这种分组预测冠状动脉疾病的严重程度,因为所有第3组或第4组患者都患有严重的冠状动脉疾病。VEST有助于评估日常活动耐受性。第1、2和3组能够耐受日常活动,而第4组则并非总是如此。通过VEST评估的缺血期间心输出量增加的程度可能是运动耐受性的有用指标之一。总之,VEST对于评估缺血性心脏病患者在各种运动期间的心脏功能非常有用。