Shahunja K M, Ahmed Tahmeed, Faruque Abu Syeed Golam, Shahid Abu Sadat Mohammad Sayeem Bin, Das Sumon Kumar, Shahrin Lubaba, Hossain Md Iqbal, Islam Md Munirul, Chisti Mohammod Jobayer
International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Glob Pediatr Health. 2016 Mar 4;3:2333794X16634267. doi: 10.1177/2333794X16634267. eCollection 2016.
We aimed to evaluate the factors associated with nosocomial infections (NIs) in under-5 children and in bacterial isolates from their blood, urine, and stool. We reviewed all under-5 hospitalized children with clinically diagnosed NIs in the inpatient ward at Dhaka Hospital of International Centre for Diarrhoeal Disease Research, Bangladesh, between January and December 2012. Comparison was made among the children with (cases = 71) and without NI (controls = 142). NI was defined as the development of new infection 48 hours after admission. Bacterial isolates in urine, blood, and stool were found in 11/52 (21%), 9/69 (13%), and 2/16 (12%) respectively. In logistic regression analysis, the children with NI were independently associated with severe acute malnutrition, congenital anomaly, invasive diarrhea, urinary tract infection on admission, and use of intravenous cannula during hospitalization. Thus, identification of these simple clinical parameters may help in preventive measures being taken to reduce the rate of NIs in such children.
我们旨在评估5岁以下儿童医院感染(NI)及其血液、尿液和粪便细菌分离株中的相关因素。我们回顾了2012年1月至12月期间在孟加拉国腹泻病研究国际中心达卡医院住院病房中所有临床诊断为NI的5岁以下住院儿童。对患有NI(病例=71)和未患NI(对照=142)的儿童进行了比较。NI定义为入院48小时后出现的新感染。尿液、血液和粪便中的细菌分离株分别在11/52(21%)、9/69(13%)和2/16(12%)中发现。在逻辑回归分析中,患有NI的儿童与重度急性营养不良、先天性异常、侵袭性腹泻、入院时的尿路感染以及住院期间使用静脉插管独立相关。因此,识别这些简单的临床参数可能有助于采取预防措施以降低此类儿童的NI发生率。