Zhao Hua, Wang Xiaoting, Liu Dawei, Zhang Hongmin, He Huaiwu, Long Yun
Zhonghua Yi Xue Za Zhi. 2015 Dec 15;95(47):3843-7.
To evaluate the diagnostic value and potential therapeutic impact of Peking Union Medical College Hospital critical ultrasonic management (PCUM) in the early management of critically ill patients with acute respiratory failure (ARF).
Patients admitted into the ICU of Peking Union Medical College Hospital for ARF were consecutively recruited over a 18-month period. Patients were randomly divided into conventional group and PCUM group (critical care ultrasonic examination was added in addition to conventional examinations). The two groups were compared with respect to time to preliminary diagnosis, time to final diagnosis, diagnostic accuracy, time to treatment response, time to other examination.
A total of 187 patients were included in this study. The two groups showed no significant differences in general clinical information or final diagnosis (P > 0.05). The PCUM group had a shorter time to preliminary diagnosis, time to final diagnosis, time to treatment response, time to X-ray/CT examination, and a higher diagnostic accuracy than the conventional group (P < 0.001). PCUM had high sensitivity and specificity for the diagnosis of acute respiratory distress syndrome (ARDS) (sensitivity 92.0%, specificity 98.5%), acute pulmonary edema (sensitivity 94.7%, specificity 96.1%), pulmonary consolidation (sensitivity 85.7%, specificity 98.6%), COPD/asthma (sensitivity 84.2%, specificity 98.7%).
The PCUM is seem to be an attractive complementary diagnostic tool and able to contribute to an early therapeutic decision for the patients with ARF.
评估北京协和医院重症超声管理(PCUM)在急性呼吸衰竭(ARF)危重症患者早期管理中的诊断价值及潜在治疗影响。
连续纳入北京协和医院重症监护病房(ICU)收治的ARF患者,为期18个月。患者随机分为常规组和PCUM组(在常规检查基础上增加重症超声检查)。比较两组的初步诊断时间、最终诊断时间、诊断准确性、治疗反应时间、其他检查时间。
本研究共纳入187例患者。两组在一般临床信息或最终诊断方面无显著差异(P>0.05)。PCUM组的初步诊断时间、最终诊断时间、治疗反应时间、X线/CT检查时间均短于常规组,诊断准确性高于常规组(P<0.001)。PCUM对急性呼吸窘迫综合征(ARDS)(敏感性92.0%,特异性98.5%)、急性肺水肿(敏感性94.7%,特异性96.1%)、肺实变(敏感性85.7%,特异性98.6%)、慢性阻塞性肺疾病/哮喘(敏感性84.2%,特异性98.7%)的诊断具有高敏感性和特异性。
PCUM似乎是一种有吸引力的辅助诊断工具,能够为ARF患者的早期治疗决策提供帮助。