Palchetti Ilaria
Dipartimento di Chimica Ugo Schiff, Università di Firenze, Firenze, Italy.
Mini Rev Med Chem. 2016;16(14):1125-33. doi: 10.2174/1389557516666160623101511.
A biosensor is a self-contained integrated device, which is capable of providing specific quantitative or semiquantitative analytical information using a biological (or biomimetic) recognition element, which is retained in direct spatial contact with an electrochemical transduction element. One of the main features of biosensors is the remarkable selectivity that their biological components confer on them. Enzymes are the most common and well-developed recognition system of the family known as catalytic biosensors. This mini-review is focused on enzyme-based biosensors for medical applications. In particular, the new trends for the technology are described. A special emphasis is devoted to the non-invasive and painless monitoring of body metabolites, such as glucose.
生物传感器是一种独立的集成设备，它能够利用生物（或仿生）识别元件提供特定的定量或半定量分析信息，该识别元件与电化学传感元件保持直接的空间接触。生物传感器的主要特点之一是其生物组件赋予它们的卓越选择性。酶是催化生物传感器家族中最常见且发展最完善的识别系统。本综述聚焦于用于医学应用的基于酶的生物传感器。特别描述了该技术的新趋势。特别强调了对身体代谢物（如葡萄糖）的非侵入性和无痛监测。
