Dişibeyaz Selçuk, Suna Nuretdin, Kuzu Ufuk Barış, Saygılı Fatih, Öztaş Erkin, Ödemiş Bülent, Önal İbrahim Koral, Kılıç Zeki Mesut Yalın, Akdoğan Meral, Kayaçetin Ertuğrul
Turkiye Yuksek Ihtisas Education and Research Hospital, Department of Gastroenterology, M.D.
Turkiye Yuksek Ihtisas Education and Research Hospital, Department of Gastroenterology, M.D..
Eur J Intern Med. 2016 Sep;33:108-11. doi: 10.1016/j.ejim.2016.06.011. Epub 2016 Jun 20.
Double Balloon Enteroscopy (DBE) provides the opportunity not only to investigate but also apply endoscopic therapeutic interventions for small intestinal disturbances. The aim of this study is to assess the indications, diagnosis, therapeutic interventions, complications and safety in clinical practise of DBE procedures that have been performed in our clinic.
MATERIAL-METHODS: The data of patients who had undergone DBE procedure in our clinic between October 2007 and December 2014 were retrospectively investigated. All features including indications, findings, histopathological results, applied interventions and complications due to procedure were noted.
A total of 297 patients, 160 (53,9%) male and 137 (46,1%) female were enrolled in the study. Total number of procedures for these 297 patients were 372 [256 (68,8%) oral and 116 (31,2%) anal]. Mean age of the patients was 46,9 (14-94) years. The most common indications were; obscure gastrointestinal (GI) bleeding (28,3%), iron deficiency anaemia (17,5% ) and abnormal findings in a prior imaging study (13,8%), respectively. The rate of new diagnosis with DBE was 11.8%, where the rate for confirmation of a possible diagnosis was 16.2%, rate of endoscopic treatment with definite diagnosis was 11%, rate for ruling out possible diagnosis or showing normal findings was 34.7% and rate for insufficient or unsuccessful procedures was 26.3%. Ulcers, inflammation and erosions (13%), polyposis syndromes (9.8%) and vascular pathologies (7.4%) were the most common endoscopic findings.
Our study shows that DBE has high efficacy for diagnosis and ability to perform treatment of small intestinal disturbances with safety.
双气囊小肠镜检查（DBE）不仅为小肠疾病的检查提供了机会，也为内镜治疗干预提供了可能。本研究旨在评估我院临床实践中DBE操作的适应证、诊断、治疗干预、并发症及安全性。
回顾性研究2007年10月至2014年12月在我院接受DBE操作的患者资料。记录所有特征，包括适应证、检查结果、组织病理学结果、实施的干预措施及操作相关并发症。
本研究共纳入297例患者，其中男性160例（53.9%），女性137例（46.1%）。这297例患者的操作总数为372次[经口256次（68.8%），经肛116次（31.2%）]。患者的平均年龄为46.9岁（14 - 94岁）。最常见的适应证分别为：不明原因的胃肠道（GI）出血（28.3%）、缺铁性贫血（17.5%）和既往影像学检查异常（13.8%）。DBE的新诊断率为11.8%，可能诊断的确诊率为16.2%，明确诊断后的内镜治疗率为11%，排除可能诊断或显示正常结果的比例为34.7%，操作不足或失败的比例为26.3%。溃疡、炎症和糜烂（13%）、息肉综合征（9.8%）和血管病变（7.4%）是最常见的内镜检查结果。
我们的研究表明，DBE在诊断小肠疾病及安全实施小肠疾病治疗方面具有较高的效能。
