核糖体RNA基因在鸟类卵子发生中的功能。

Ribosomal RNA gene functioning in avian oogenesis.

作者信息

Koshel Elena, Galkina Svetlana, Saifitdinova Alsu, Dyomin Alexandr, Deryusheva Svetlana, Gaginskaya Elena

机构信息

Department of Cytology and Histology, Saint-Petersburg State University, Saint-Petersburg, 199034, Russia.

Department of Embryology, Carnegie Institution for Science, Baltimore, MD 21218, USA.

出版信息

Cell Tissue Res. 2016 Dec;366(3):533-542. doi: 10.1007/s00441-016-2444-4. Epub 2016 Jun 23.

DOI:10.1007/s00441-016-2444-4

PMID:27339801

Abstract

Despite long-term exploration into ribosomal RNA gene functioning during the oogenesis of various organisms, many intriguing problems remain unsolved. In this review, we describe nucleolus organizer region (NOR) activity in avian oocytes. Whereas oocytes from an adult avian ovary never reveal the formation of the nucleolus in the germinal vesicle (GV), an ovary from juvenile birds possesses both nucleolus-containing and non-nucleolus-containing oocytes. The evolutionary diversity of oocyte NOR functioning and the potential non-rRNA-related functions of the nucleolus in oocytes are also discussed.

摘要

尽管长期以来一直在探索核糖体RNA基因在各种生物体卵子发生过程中的功能，但许多有趣的问题仍未得到解决。在这篇综述中，我们描述了鸟类卵母细胞中的核仁组织区（NOR）活性。成年鸟类卵巢中的卵母细胞在生发泡（GV）中从未显示出核仁的形成，而幼鸟的卵巢中既有含核仁的卵母细胞，也有不含核仁的卵母细胞。我们还讨论了卵母细胞NOR功能的进化多样性以及卵母细胞核仁潜在的非rRNA相关功能。