Pinter Nandor K, McVige Jennifer, Mechtler Laszlo
Dent Neurologic Institute, 3980 Sheridan Drive, Amherst, NY, 14226, USA.
National Institute of Clinical Neurosciences, Amerikai ut 57, Budapest, 1145, Hungary.
Curr Pain Headache Rep. 2016 Aug;20(8):49. doi: 10.1007/s11916-016-0580-x.
The congenital and acquired deformities of the craniovertebral junction (CVJ), such as basilar invagination, basilar impression, or platybasia, can present in the form of slowly progressive or acute neurologic deterioration. In many cases, an insidious headache is the only symptom and can be a diagnostic challenge for the neurologist. Proper imaging studies as well as recognizing often associated neurologic or systemic conditions are required for early diagnosis and effective therapy. In the current report, the primary focus will be on clinical aspects of these CVJ abnormalities; the pathologic and radiologic aspects, such as developmental and pathophysiologic background or radiographic analysis, will be discussed briefly, confined to clinically relevant data.
颅颈交界区（CVJ）的先天性和后天性畸形，如基底凹陷、基底压迹或扁平颅底，可表现为缓慢进展或急性神经功能恶化。在许多情况下，隐匿性头痛是唯一症状，对神经科医生来说可能是一个诊断挑战。早期诊断和有效治疗需要进行适当的影像学检查以及识别常见的相关神经或全身疾病。在本报告中，主要关注这些CVJ异常的临床方面；病理和放射学方面，如发育和病理生理背景或影像学分析，将简要讨论，仅限于临床相关数据。
