Singh Hemindermeet, Luni Faraz Khan, Marwaha Bharat, Ali Syed Sohail, Alo Mohammed
Cardiovascular Fellowship Program, Mercy St. Vincent Medical Center, Toledo, Ohio, USA.
Cardiology. 2016;135(3):160-163. doi: 10.1159/000446574. Epub 2016 Jun 25.
Pyrethroids are the major components of various commercially used insect repellants. These are less toxic to humans due to their slow absorption and rapid metabolism. However, cases of suicidal and accidental poisoning with household insecticides are not uncommon. We report a case of a 59-year-old female who presented with syncope after an accidental exposure to bed bug repellant spray at home. She was found to be in complete heart block and was treated conservatively. There was complete resolution of symptoms and atrioventricular conduction abnormality on day 2 of hospitalization. She was discharged in a stable condition with an uneventful follow-up course. Cardiac involvement in pyrethroid toxicity is rare. We describe various clinical manifestations and the pathophysiology of toxicity caused by pyrethroid-containing insecticides.
拟除虫菊酯是各种商业用途驱虫剂的主要成分。由于其吸收缓慢和代谢迅速,对人类毒性较低。然而,家用杀虫剂导致自杀和意外中毒的情况并不罕见。我们报告一例59岁女性,在家中意外接触臭虫驱避喷雾后出现晕厥。她被发现处于完全性心脏传导阻滞,接受了保守治疗。住院第2天症状和房室传导异常完全消失。她出院时病情稳定,随访过程顺利。拟除虫菊酯中毒导致心脏受累较为罕见。我们描述了含拟除虫菊酯杀虫剂所致毒性的各种临床表现和病理生理学。