Bartnicka Anna, Szachta Patrycja, Gałecka Mirosława
Pomeranian J Life Sci. 2015;61(3):282-6.
The intestinal microbiota, either directly or indirectly, plays an important role in maintaining the homeostasis of the body. The intestine microorganisms are significant due to the role they play in stimulating the development of the immune system, protecting against pathogens, and also managing metabolic and nutrient processing. The effectiveness of probiotics and prebiotics in various gastrointestinal diseases has been repeatedly confirmed. However, increasing interest in faecal transplantation has also been observed. Its efficacy in the treatment of pseudomembranous colitis has been repeatedly demonstrated. More often this method is discussed regarding the possibility of using it in other diseases linked with dysbiosis. Faecal microbiota transplantation, because of its rapid efficacy, minimal risk and adverse effects, relatively low cost, and the ability to re-establish the correct intestinal microbiota profile, could be an alternative treatment method in several other diseases. This paper will introduce the latest therapeutic aspects of microbiota transplantation, including its implications in the treatment of gastrointestinal diseases.
肠道微生物群直接或间接地在维持机体稳态中发挥重要作用。肠道微生物因其在刺激免疫系统发育、抵御病原体以及管理代谢和营养加工方面所起的作用而意义重大。益生菌和益生元在各种胃肠道疾病中的有效性已得到反复证实。然而，人们对粪便移植的兴趣也在不断增加。其在治疗伪膜性结肠炎方面的疗效已得到反复证明。人们更多地讨论了将该方法用于其他与菌群失调相关疾病的可能性。粪便微生物群移植因其疗效迅速、风险和不良反应极小、成本相对较低以及能够重建正确的肠道微生物群谱，可能成为其他几种疾病的替代治疗方法。本文将介绍微生物群移植的最新治疗方面，包括其在胃肠道疾病治疗中的意义。
