Atarguine H, Hocar O, Hamdaoui A, Akhdari N, Amal S
Service de dermatologie, hôpital Errazi, CHU Mohamed VI, faculté de médecine et pharmacie, université Cadi Ayyad, 53, rue Assif-D., 40000 Marrakech, Maroc.
Service de dermatologie, hôpital Errazi, CHU Mohamed VI, faculté de médecine et pharmacie, université Cadi Ayyad, 53, rue Assif-D., 40000 Marrakech, Maroc.
Arch Pediatr. 2016 Aug;23(8):832-5. doi: 10.1016/j.arcped.2016.05.006. Epub 2016 Jun 23.
Frontal fibrosing alopecia is a topographic form of lichen planopilaris, which most commonly affects postmenopausal women. We report on three original pediatric cases of this scarring alopecia, including one case of female twins.
The first observation concerns twin sisters, 14 years of age, with frontotemporal symmetric and progressive alopecia, beginning at the age of 5 years, with follicular facial noninflammatory micropapules. Histological examination showed a depletion of hair follicles with dermal fibrosis and perivascular infiltrate. The treatment decided was monthly intralesional infiltrations of betamethasone. The second case is a 7-year-old girl, with a frontotemporal alopecia band and partial alopecia of the eyebrows. Histological examination was consistent with lichen planopilaris. The outcome was favorable after six monthly oral boluses of steroids.
The initial description of frontal fibrosing alopecia was made in postmenopausal women. Some cases have been reported subsequently in premenopausal women as well as in men, with recent identification of familial cases. To our knowledge, these are the first pediatric cases of this form of alopecia, which is not only postmenopausal.
额部纤维性秃发是扁平苔藓性毛囊病的一种局部表现形式，最常见于绝经后女性。我们报告了3例这种瘢痕性秃发的儿童原始病例，其中包括1例女性双胞胎病例。
第一例观察对象是一对14岁的双胞胎姐妹，自5岁起出现额颞部对称性进行性脱发，伴有面部毛囊性非炎性微丘疹。组织学检查显示毛囊缺失，伴有真皮纤维化和血管周围浸润。决定的治疗方法是每月进行一次倍他米松皮损内注射。第二例是一名7岁女孩，有额颞部脱发带和部分眉毛脱落。组织学检查符合扁平苔藓性毛囊病。在每月口服6次类固醇大剂量药物后，病情转好。
额部纤维性秃发最初是在绝经后女性中描述的。随后在绝经前女性以及男性中也有一些病例报道，最近还发现了家族性病例。据我们所知，这些是这种秃发形式的首批儿童病例，而不仅限于绝经后女性。
