Lis-Święty Anna, Brzezińska-Wcisło Ligia
Department of Dermatology, School of Medicine, Medical University of Silesia, Katowice, Poland.
Postepy Dermatol Alergol. 2020 Aug;37(4):482-489. doi: 10.5114/ada.2020.98241. Epub 2020 Sep 2.
Frontal fibrosing alopecia (FFA) is recognized to represent a generalized process of inflammatory scarring alopecia. Apart from the classic form affecting the frontal hairline, there are a range of disease manifestations involving loss of eyebrows and of eyelashes, loss of peripheral body hair, fibrosing alopecia in a pattern distribution, facial and extrafacial skin, mucous membrane, and nail involvement. Classic linear, diffuse "zigzag", pseudo "fringe sign", androgenetic alopecia-like, cockade-like, ophiasis-like and incomplete patterns are distinguished. The aetiology of FFA remains obscure, but a number of pathogenetic hypotheses and treatments to halt disease progression have been proposed.
额部纤维性秃发（FFA）被认为是一种炎症性瘢痕性秃发的全身性过程。除了影响额发际线的经典形式外，还有一系列疾病表现，包括眉毛和睫毛脱落、身体外周毛发脱落、斑片状分布的纤维性秃发、面部和面部以外皮肤、黏膜及指甲受累。可区分出经典的线性、弥漫性“之字形”、假性“边缘征”、雄激素性秃发样、帽状、匐行性样及不完全型等模式。FFA的病因仍不明确，但已提出了一些发病机制假说及阻止疾病进展的治疗方法。
