Psychosis Following an Increase in Intrathecal Baclofen.

作者信息

Maneyapanda Mithra B, Driver Sangeeta Patel, Ripley David L, Lloyd Robert, Brkic Nenad

机构信息

Department of Physical Medicine and Rehabilitation, Northwestern University Feinberg School of Medicine and Rehabilitation Institute of Chicago, Chicago, IL(∗).

Department of Physical Medicine and Rehabilitation, Northwestern University Feinberg School of Medicine and Rehabilitation Institute of Chicago, Chicago, IL(†).

出版信息

PM R. 2016 Dec;8(12):1222-1224. doi: 10.1016/j.pmrj.2016.06.018. Epub 2016 Jun 23.

DOI:10.1016/j.pmrj.2016.06.018

PMID:27346089

Abstract

UNLABELLED

Baclofen is a commonly used medication to treat spasticity in neurologic disorders. In the traumatic brain injury (TBI) population, the intrathecal administration of baclofen is often preferred over oral administration due to cognitive side effects. Here we report on a case of a psychotic episode following an increase in intrathecal baclofen in a young man with a history of a TBI. Although intrathecal baclofen is commonly used and is generally well tolerated, this case highlights an important potential effect of intrathecal baclofen that has rarely been reported in the literature.