腹腔内使用依托泊苷治疗后恶性小肠梗阻的缓解
Resolution of malignant small bowel obstruction after intraperitoneal etoposide therapy.
作者信息
Fanning J, Daugherty J P, Weese J L
机构信息
Department of Surgical Oncology, Fox Chase Cancer Center, Philadelphia, Pa. 19111.
出版信息
South Med J. 1989 Jun;82(6):798-9. doi: 10.1097/00007611-198906000-00035.
Abstract
In the case we have reported, abdominal carcinomatosis with malignant small bowel obstruction (due to metastatic lung adenocarcinoma) developed despite ten cycles of cisplatinvinblastine and eight months of treatment with interferon and interleukin-2. Etoposide (VP-16) administered intraperitoneally as part of a phase I trial produced dramatic relief of the obstruction.
摘要
在我们报道的病例中，尽管接受了10个周期的顺铂-长春花碱治疗以及8个月的干扰素和白细胞介素-2治疗，但仍发生了伴有恶性小肠梗阻（由转移性肺腺癌引起）的腹部癌转移。作为一项I期试验的一部分，腹腔内给予依托泊苷（VP-16）使梗阻症状得到了显著缓解。
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