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病例报告:垂体特发性巨细胞肉芽肿——全垂体功能减退的罕见病因

Case report: idiopathic giant cell granuloma of the hypophysis: an unusual cause of panhypopituitarism.

作者信息

Siqueira E, Tsung J S, Al-Kawi M Z, Woodhouse N

机构信息

Department of Neurosciences, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.

出版信息

Surg Neurol. 1989 Jul;32(1):68-71. doi: 10.1016/0090-3019(89)90039-6.

DOI:10.1016/0090-3019(89)90039-6
PMID:2734692
Abstract

A 37-year-old man presented with headache and reduced libido. He suffered from panhypopituitarism, and the walls of the pituitary fossa were noted to be thickened, sclerotic, and irregular. Computed tomography scans showed an intrasellar and suprasellar, patchy enhancing tumor. From a biopsy taken at transsphenoidal surgery, a giant cell granuloma was diagnosed, for which there was no obvious cause. Inflammatory disease within the pituitary fossa should be suspected if a reaction is seen in the surrounding bone.

摘要

一名37岁男性出现头痛和性欲减退症状。他患有全垂体功能减退症,发现垂体窝壁增厚、硬化且不规则。计算机断层扫描显示鞍内和鞍上有斑片状强化肿瘤。经蝶窦手术活检诊断为巨细胞肉芽肿,病因不明。如果在周围骨质中发现反应,应怀疑垂体窝内存在炎症性疾病。

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Case report: idiopathic giant cell granuloma of the hypophysis: an unusual cause of panhypopituitarism.病例报告:垂体特发性巨细胞肉芽肿——全垂体功能减退的罕见病因
Surg Neurol. 1989 Jul;32(1):68-71. doi: 10.1016/0090-3019(89)90039-6.
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引用本文的文献

1
Pituitary granuloma and chronic inflammation of hypophysis: clinical and immunohistochemical studies.垂体肉芽肿与垂体慢性炎症:临床与免疫组织化学研究
Acta Neurochir (Wien). 1993;121(3-4):152-8. doi: 10.1007/BF01809268.
2
Pituitary granuloma and pyoderma gangrenosum.垂体肉芽肿与坏疽性脓皮病。
J Endocrinol Invest. 1990 Sep;13(8):677-81. doi: 10.1007/BF03349595.
3
Non-specific granulomas of the pituitary: report of six cases treated surgically.垂体非特异性肉芽肿:6例手术治疗报告
Neurosurg Rev. 1991;14(3):185-90. doi: 10.1007/BF00310655.