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[20-甲基胆蒽诱导致癌过程中C3HA品系小鼠脾细胞的自然杀伤活性]

[Natural killer activity of the splenocytes in C3HA strain mice during 20-methylcholanthrene-induced carcinogenesis].

作者信息

Pogodina O N, Malygin A M, Goriunova L B, Fel' V Ia

出版信息

Tsitologiia. 1989 Feb;31(2):220-5.

PMID:2734852
Abstract

The induction of tumor in C3HA mice after intramuscular injection with 20-methylcholanthrene is accompanied by a decrease in natural antitumor resistance. This conclusion is based on the observation of the decreased natural killer activity per total number of splenocytes, from the time of carcinogen application till the appearance of tumor nodes.

摘要

给C3HA小鼠肌肉注射20-甲基胆蒽后诱发肿瘤,同时天然抗肿瘤抵抗力下降。这一结论基于从应用致癌物之时到出现肿瘤结节期间,每单位脾细胞总数的自然杀伤活性降低这一观察结果。

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