Halkier-Sørensen L, Andresen J H
Ugeskr Laeger. 1989 May 8;151(19):1191-2.
The case is presented of a 33-year-old man treated with Roaccutane for two years on account of severe acne conglobata. X-ray examination after two years showed pronounced hyperostoses with bridging in the thoracic spine and hyperostoses and beginning bridging in the cervical spine. Furthermore, small exostoses were found on the hands and feet. X-ray control of patients treated for more than six months with Roaccutane is recommended.
本文报告了一名33岁男性因重度聚合性痤疮接受异维甲酸治疗两年的病例。两年后的X线检查显示胸椎有明显的骨肥厚及骨桥形成，颈椎有骨肥厚及骨桥形成的初期表现。此外，在手部和足部发现了小的外生骨疣。建议对接受异维甲酸治疗超过六个月的患者进行X线检查。
