Lenkov D N, Vereshchak N I
Zh Vyssh Nerv Deiat Im I P Pavlova. 1989 Jan-Feb;39(1):118-27.
Quantitative locomotion changes have been studied in the norm and in different periods after local ablation of motor projection of hind paw in the right hemisphere of 5-16 weeks white rats. The length and width of step gradually increase with the age, and coefficients of gait asymmetry reflecting individual characteristics, are relatively stable in intact animals. Local decortication is accompanied by significant shifts of all locomotion parameters clearly expressed in the first days after ablation. The most sensitive characteristic of gait anomaly is the standard deviation of half-step. In 5 weeks after ablation a lag is observed of operated rats behind the control ones in all parameters. Load application contributes to revealing of locomotion parameters shifts from the norm in later periods after decortication. In 9 and 11 weeks after surgery, the signs of supercompensation are observed in a number of parameters.
在5至16周龄的白鼠右半球局部损毁后爪运动投射的正常状态及不同时期,对定量运动变化进行了研究。步长和步宽随年龄逐渐增加,反映个体特征的步态不对称系数在未受损动物中相对稳定。局部去皮质术伴随着所有运动参数在损毁后最初几天明显的显著变化。步态异常最敏感的特征是半步的标准差。损毁后5周,观察到手术大鼠在所有参数上落后于对照大鼠。施加负荷有助于揭示去皮质术后后期运动参数与正常状态的差异。术后9周和11周,在一些参数中观察到超代偿的迹象。