Amin Zulkifli, Amin Hilman Zulkifli, Tedyanto Nadim Marchian
Rom J Intern Med. 2016 Apr-Jun;54(2):93-7. doi: 10.1515/rjim-2016-0015.
Hepatopulmonary syndrome (HPS) is a pulmonary complication of liver disease characterized by arterial hypoxemia. Mechanisms related to this event are diffusion-perfusion flaw, ventilation-perfusion (V/Q) mismatch, and direct arteriovenous shunts. Diagnosis of HPS is based on the presence of liver disease or portal hypertension, increased alveolar-arterial (A-a) PO2, and intrapulmonary vascular dilatations (IPVD). Lung transplantation (LT) remains the most effective therapy for HPS. In spite of its poor prognosis, we could improve the quality of life and survival rate of patients.
肝肺综合征（HPS）是一种以动脉血氧不足为特征的肝脏疾病肺部并发症。与此病症相关的机制包括弥散-灌注缺陷、通气-灌注（V/Q）不匹配以及直接动静脉分流。HPS的诊断基于肝脏疾病或门静脉高压的存在、肺泡-动脉（A-a）氧分压升高以及肺内血管扩张（IPVD）。肺移植（LT）仍然是治疗HPS最有效的方法。尽管预后较差，但我们可以提高患者的生活质量和生存率。
