Smith R P
Department of Obstetrics and Gynecology, Medical College of Georgia, Augusta 30912.
Am J Obstet Gynecol. 1989 Jun;160(6):1400-3; discussion 1403-5. doi: 10.1016/0002-9378(89)90861-2.
Three-dimensional pressure-velocity (slope) topograms may be constructed to evaluate the uterine muscle's ability to contract under varying conditions of pressure load in vivo. This type of analysis indicates that even at intrauterine pressures that greatly exceed perfusion pressure, the uterus is capable of rates of change as high as +/- 120 mm Hg/sec. The topograms of dysmenorrheic women appear similar among women and from month to month. Dramatic differences in the topograms are noted before the development of menstrual pain and after nonsteroidal antiinflammatory drug therapy. This suggests a possible causal relationship to the pain of dysmenorrhea. These topograms may also represent a sensitive measure of physiology and therapeutic effects.
可以构建三维压力-速度（斜率）拓扑图，以评估子宫肌层在体内不同压力负荷条件下的收缩能力。这类分析表明，即使子宫内压力大大超过灌注压力，子宫仍能够产生高达±120毫米汞柱/秒的变化率。痛经女性的拓扑图在不同女性之间以及不同月份看起来相似。在痛经发作前和非甾体抗炎药治疗后，拓扑图存在显著差异。这表明其与痛经疼痛之间可能存在因果关系。这些拓扑图也可能是生理和治疗效果的一种敏感指标。
