• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Evidence for a "metabolically inactive" inorganic phosphate pool in adenosine triphosphate synthase reaction using localized 31P saturation transfer magnetic resonance spectroscopy in the rat brain at 11.7 T.在11.7T磁场下，利用局部31P饱和转移磁共振波谱法在大鼠脑中研究三磷酸腺苷合酶反应中“代谢不活跃”的无机磷酸池的证据。
J Cereb Blood Flow Metab. 2016 Sep;36(9):1513-8. doi: 10.1177/0271678X16657095. Epub 2016 Jun 28.
2
In vivo evidence for cerebral bioenergetic abnormalities in schizophrenia measured using 31P magnetization transfer spectroscopy.使用 31P 磁共振波谱技术测量精神分裂症脑能量代谢异常的活体证据。
JAMA Psychiatry. 2014 Jan;71(1):19-27. doi: 10.1001/jamapsychiatry.2013.2287.
3
A phosphorus-31 nuclear magnetic resonance study of effects of altered thyroid state on cardiac bioenergetics.
Adv Myocardiol. 1985;6:299-309.
4
Quantitative ATP synthesis in human liver measured by localized 31P spectroscopy using the magnetization transfer experiment.使用磁化转移实验通过局部31P光谱法测量人肝脏中的定量ATP合成。
NMR Biomed. 2008 Jun;21(5):437-43. doi: 10.1002/nbm.1207.
5
Cerebral metabolism in experimental hydrocephalus: an in vivo 1H and 31P magnetic resonance spectroscopy study.实验性脑积水的脑代谢：一项体内氢质子和磷-31磁共振波谱研究
J Neurosurg. 1999 Oct;91(4):660-8. doi: 10.3171/jns.1999.91.4.0660.
6
P magnetization transfer magnetic resonance spectroscopy: Assessing the activation induced change in cerebral ATP metabolic rates at 3 T.P 磁化转移磁共振波谱：在 3T 下评估大脑 ATP 代谢率的激活诱导变化。
Magn Reson Med. 2018 Jan;79(1):22-30. doi: 10.1002/mrm.26663. Epub 2017 Mar 16.
7
Developmental changes of phosphorus metabolite concentrations in the human brain: a 31P magnetic resonance spectroscopy study in vivo.人脑磷代谢物浓度的发育变化：一项体内31P磁共振波谱研究
Pediatr Res. 1994 Apr;35(4 Pt 1):431-5.
8
Measurements of in vivo 31P nuclear magnetic resonance spectra in neuroectodermal tumors for the evaluation of the effects of chemotherapy.测量神经外胚层肿瘤的体内31P核磁共振光谱以评估化疗效果。
Cancer Res. 1985 Jun;45(6):2429-33.
9
Cellular applications of 31P and 13C nuclear magnetic resonance.31P和13C核磁共振的细胞应用
Science. 1979 Jul 13;205(4402):160-6. doi: 10.1126/science.36664.
10
Heterogeneous metabolic changes in the calf muscle of the rat during ischaemia-reperfusion: in vivo analysis by 31P nuclear magnetic resonance chemical shift imaging and 1H magnetic resonance imaging.大鼠小腿肌肉在缺血再灌注期间的异质性代谢变化：通过31P核磁共振化学位移成像和1H磁共振成像进行体内分析。
Cardiovasc Surg. 1993 Aug;1(4):337-42.

引用本文的文献

1
Use of P magnetisation transfer magnetic resonance spectroscopy to measure ATP changes after 670 nm transcranial photobiomodulation in older adults.使用 P 磁化转移磁共振波谱测量老年人经 670nm 经颅光生物调节后的 ATP 变化。
Aging Cell. 2023 Nov;22(11):e14005. doi: 10.1111/acel.14005. Epub 2023 Oct 6.
2
Accumulation of 3-aminopropylphosphonate in the ex vivo brain observed by phosphorus-31 nuclear magnetic resonance.通过磷-31 核磁共振观察到 3-氨基丙膦酸盐在体外脑中的积累。
NMR Biomed. 2022 Aug;35(8):e4721. doi: 10.1002/nbm.4721. Epub 2022 Mar 13.
3
Magnetic resonance spectroscopy in the rodent brain: Experts' consensus recommendations.啮齿动物大脑中的磁共振波谱：专家共识建议。
NMR Biomed. 2020 Aug 26:e4325. doi: 10.1002/nbm.4325.
4
Unveiling a hidden P signal coresonating with extracellular inorganic phosphate by outer-volume-suppression and localized P MRS in the human brain at 7T.在 7T 人体大脑中，通过外体积抑制和局部磷磁共振波谱（P MRS）揭示与细胞外无机磷酸盐共振的隐藏 P 信号核心。
Magn Reson Med. 2018 Oct;80(4):1289-1297. doi: 10.1002/mrm.27121. Epub 2018 Feb 9.
5
P T s of phosphomonoesters, phosphodiesters, and inorganic phosphate in the human brain at 7T.在 7T 下测量人脑内的磷酸单酯、磷酸二酯和无机磷酸盐的 P T 值。
Magn Reson Med. 2018 Jul;80(1):29-35. doi: 10.1002/mrm.27026. Epub 2017 Dec 7.
6
Rapid and simultaneous measurement of phosphorus metabolite pool size ratio and reaction kinetics of enzymes in vivo.在体快速同步测量磷代谢物池大小比率和酶反应动力学。
J Magn Reson Imaging. 2018 Jan;47(1):210-221. doi: 10.1002/jmri.25744. Epub 2017 May 8.
7
P magnetization transfer magnetic resonance spectroscopy: Assessing the activation induced change in cerebral ATP metabolic rates at 3 T.P 磁化转移磁共振波谱：在 3T 下评估大脑 ATP 代谢率的激活诱导变化。
Magn Reson Med. 2018 Jan;79(1):22-30. doi: 10.1002/mrm.26663. Epub 2017 Mar 16.
8
Imaging and spectroscopic approaches to probe brain energy metabolism dysregulation in neurodegenerative diseases.用于探究神经退行性疾病中脑能量代谢失调的成像和光谱学方法。
J Cereb Blood Flow Metab. 2017 Jun;37(6):1927-1943. doi: 10.1177/0271678X17697989. Epub 2017 Mar 9.
9
Efficient P band inversion transfer approach for measuring creatine kinase activity, ATP synthesis, and molecular dynamics in the human brain at 7 T.在 7T 下测量人类大脑中肌酸激酶活性、ATP 合成和分子动力学的高效 P 带反转传递方法。
Magn Reson Med. 2017 Nov;78(5):1657-1666. doi: 10.1002/mrm.26560. Epub 2016 Nov 20.

本文引用的文献

1
(31)P-MRS of healthy human brain: ATP synthesis, metabolite concentrations, pH, and T1 relaxation times.健康人脑的磷磁共振波谱分析：ATP合成、代谢物浓度、pH值及T1弛豫时间
NMR Biomed. 2015 Nov;28(11):1455-62. doi: 10.1002/nbm.3384. Epub 2015 Sep 24.
2
Quantification of in vivo ³¹P NMR brain spectra using LCModel.使用LCModel对活体³¹P NMR脑谱进行定量分析。
NMR Biomed. 2015 Jun;28(6):633-41. doi: 10.1002/nbm.3291. Epub 2015 Apr 14.
3
Amplification of the effects of magnetization exchange by (31) P band inversion for measuring adenosine triphosphate synthesis rates in human skeletal muscle.通过（31）P 带反转增强磁化交换效应以测量人体骨骼肌中三磷酸腺苷的合成速率。
Magn Reson Med. 2015 Dec;74(6):1505-14. doi: 10.1002/mrm.25514. Epub 2014 Dec 2.
4
Brain high-energy phosphates and creatine kinase synthesis rate under graded isoflurane anesthesia: An in vivo (31) P magnetization transfer study at 11.7 tesla.异氟烷分级麻醉下脑高能磷酸盐与肌酸激酶合成率：11.7特斯拉的体内³¹P磁化转移研究
Magn Reson Med. 2015 Feb;73(2):726-30. doi: 10.1002/mrm.25136. Epub 2014 Feb 12.
5
Halogenated volatile anesthetics alter brain metabolism as revealed by proton magnetic resonance spectroscopy of mice in vivo.卤代挥发性麻醉剂通过对活体小鼠的质子磁共振波谱分析改变脑代谢。
Neuroimage. 2013 Apr 1;69:244-55. doi: 10.1016/j.neuroimage.2012.12.020. Epub 2012 Dec 21.
6
³¹P-magnetization transfer magnetic resonance spectroscopy measurements of in vivo metabolism.³¹P 磁共振波谱测量活体代谢物的磁化转移。
Diabetes. 2012 Nov;61(11):2669-78. doi: 10.2337/db12-0558.
7
pH as a biomarker of neurodegeneration in Huntington's disease: a translational rodent-human MRS study.pH 作为亨廷顿病神经退行性变的生物标志物：一项转化啮齿动物-人类 MRS 研究。
J Cereb Blood Flow Metab. 2012 May;32(5):771-9. doi: 10.1038/jcbfm.2012.15. Epub 2012 Feb 29.
8
Splitting of Pi and other ³¹P NMR anomalies of skeletal muscle metabolites in canine muscular dystrophy.骨骼肌代谢产物中 Pi 和其他 ³¹P NMR 异常的犬肌肉营养不良症的分裂。
NMR Biomed. 2012 Oct;25(10):1160-9. doi: 10.1002/nbm.2785. Epub 2012 Feb 22.
9
In vivo 31P MRS detection of an alkaline inorganic phosphate pool with short T1 in human resting skeletal muscle.在人体静息骨骼肌中用短 T1 检测碱性无机磷酸盐池的体内 31P MRS 检测。
NMR Biomed. 2010 Oct;23(8):995-1000. doi: 10.1002/nbm.1517.
10
Multimodal neuroimaging provides a highly consistent picture of energy metabolism, validating 31P MRS for measuring brain ATP synthesis.多模态神经成像提供了能量代谢的高度一致图像，验证了用于测量脑ATP合成的31P MRS。
Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):3988-93. doi: 10.1073/pnas.0806516106. Epub 2009 Feb 20.

在11.7T磁场下，利用局部31P饱和转移磁共振波谱法在大鼠脑中研究三磷酸腺苷合酶反应中“代谢不活跃”的无机磷酸池的证据。

Evidence for a "metabolically inactive" inorganic phosphate pool in adenosine triphosphate synthase reaction using localized 31P saturation transfer magnetic resonance spectroscopy in the rat brain at 11.7 T.

作者信息

Tiret Brice, Brouillet Emmanuel, Valette Julien

机构信息

Commissariat à l'Energie Atomique et aux Energies Alternatives (CEA), Direction de la Recherche Fondamentale (DRF), Institut d'Imagerie Biomédicale (I2BM), Molecular Imaging Research Center (MIRCen), Fontenay-aux-Roses, France Centre National de la Recherche Scientifique (CNRS), Université Paris-Saclay, UMR 9199, Neurodegenerative Diseases Laboratory, Fontenay-aux-Roses, France

Commissariat à l'Energie Atomique et aux Energies Alternatives (CEA), Direction de la Recherche Fondamentale (DRF), Institut d'Imagerie Biomédicale (I2BM), Molecular Imaging Research Center (MIRCen), Fontenay-aux-Roses, France Centre National de la Recherche Scientifique (CNRS), Université Paris-Saclay, UMR 9199, Neurodegenerative Diseases Laboratory, Fontenay-aux-Roses, France.

出版信息

J Cereb Blood Flow Metab. 2016 Sep;36(9):1513-8. doi: 10.1177/0271678X16657095. Epub 2016 Jun 28.

DOI:10.1177/0271678X16657095
PMID:27354096
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5012527/
Abstract

With the increased spectral resolution made possible at high fields, a second, smaller inorganic phosphate resonance can be resolved on (31)P magnetic resonance spectra in the rat brain. Saturation transfer was used to estimate de novo adenosine triphosphate synthesis reaction rate. While the main inorganic phosphate pool is used by adenosine triphosphate synthase, the second pool is inactive for this reaction. Accounting for this new pool may not only help us understand (31)P magnetic resonance spectroscopy metabolic profiles better but also better quantify adenosine triphosphate synthesis.

摘要

随着高场下光谱分辨率的提高，在大鼠脑的磷-31磁共振谱上可以分辨出第二个较小的无机磷酸盐共振峰。采用饱和转移技术来估计三磷酸腺苷的从头合成反应速率。虽然主要的无机磷酸盐池被三磷酸腺苷合酶利用，但第二个池对该反应无活性。考虑到这个新的池不仅可能有助于我们更好地理解磷-31磁共振波谱代谢谱，还能更好地定量三磷酸腺苷的合成。