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胆囊收缩素对绵羊垂体前叶和后叶激素释放的诱导作用

Anterior and posterior pituitary hormone release induced in sheep by cholecystokinin.

作者信息

Ebenezer I S, Thornton S N, Parrott R F

机构信息

Agricultural and Food Research Council, Institute of Animal Physiology and Genetics Research, Cambridge Research Station, United Kingdom.

出版信息

Am J Physiol. 1989 Jun;256(6 Pt 2):R1355-7. doi: 10.1152/ajpregu.1989.256.6.R1355.

DOI:10.1152/ajpregu.1989.256.6.R1355
PMID:2735459
Abstract

The effect of an intravenous bolus injection of cholecystokinin octapeptide (CCK-8; 0.85 micrograms/kg) on the release of cortisol, prolactin, vasopressin, and oxytocin was studied in sheep (n = 10). Concentrations of these hormones were measured in blood samples taken before (-10, 0 min) and after (5, 10, 20 min) administration of a saline vehicle or vehicle + CCK. Following CCK treatment, levels of cortisol were raised after 10 and 20 min, prolactin and vasopressin concentrations were increased after 5 min, and oxytocin secretion was unaffected.

摘要

研究了静脉推注八肽胆囊收缩素(CCK-8;0.85微克/千克)对绵羊(n = 10)皮质醇、催乳素、血管加压素和催产素释放的影响。在注射生理盐水或生理盐水+CCK之前(-10、0分钟)和之后(5、10、20分钟)采集血样,测量这些激素的浓度。CCK处理后,10分钟和20分钟时皮质醇水平升高,5分钟时催乳素和血管加压素浓度增加,催产素分泌未受影响。

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引用本文的文献

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The role of cholecystokinin 1 receptor in prolactin inhibited gastric emptying of male rat.胆囊收缩素 1 受体在催乳素抑制雄性大鼠胃排空中的作用。
J Neurogastroenterol Motil. 2012 Oct;18(4):385-90. doi: 10.5056/jnm.2012.18.4.385. Epub 2012 Oct 9.
2
Electrical activation and c-fos mRNA expression in rat neurosecretory neurones after systemic administration of cholecystokinin.全身注射胆囊收缩素后大鼠神经分泌神经元的电活动及c-fos mRNA表达
J Physiol. 1991 Dec;444:51-63. doi: 10.1113/jphysiol.1991.sp018865.