Uzun Ozlem, Turkmen Suha, Eryigit Umut, Mentese Ahmet, Turkyilmaz Serdar, Turedi Suleyman, Karahan Suleyman Caner, Gunduz Abdulkadir
Department of Emergency Medicine, Bagcilar Training and Research Hospital, İstanbul.
Department of Emergency Medicine, Karadeniz Technical University Faculty of Medicine, Trabzon.
Turk J Emerg Med. 2016 Feb 26;14(3):99-103. doi: 10.5505/1304.7361.2014.15679. eCollection 2014 Sep.
Biochemical markers play an important role in the early diagnosis of abdominal pain. This study aimed to investigate the diagnostic value of intestinal type fatty acid binding protein (I-FABP) in patients with abdominal pathology.
This prospective and descriptive study was performed at the University Hospital Emergency Department. Serum I-FABP levels of patients presenting with acute abdominal pain were measured at time of admission and were compared with those of healthy individuals.
The mean I-FABP level of the 171 patients enrolled in this study was 170.1±543.4 pg/ml, while that of a healthy control group was 61.4±47.4 pg/ml. Although I-FABP levels were higher in the patient group, this difference was not statistically significant (p>0.05). However, I-FABP levels of patients with mesenteric ischemia and intra-abdominal mass were significantly higher than those of healthy individuals (p≤0.05).
I-FABP levels that are evaluated at time of admission in patients presenting with abdominal pain to the emergency department are significantly higher in patients with mesenteric ischemia and intra-abdominal mass than are those of healthy individuals.
生化标志物在腹痛的早期诊断中起着重要作用。本研究旨在探讨肠型脂肪酸结合蛋白（I-FABP）在腹部疾病患者中的诊断价值。
本前瞻性描述性研究在大学医院急诊科进行。对因急性腹痛就诊的患者入院时测定血清I-FABP水平，并与健康个体进行比较。
本研究纳入的171例患者的I-FABP平均水平为170.1±543.4 pg/ml，而健康对照组为61.4±47.4 pg/ml。虽然患者组的I-FABP水平较高，但差异无统计学意义（p>0.05）。然而，肠系膜缺血和腹腔内肿块患者的I-FABP水平显著高于健康个体（p≤0.05）。
急诊科因腹痛就诊患者入院时评估的I-FABP水平，肠系膜缺血和腹腔内肿块患者显著高于健康个体。
