[蒙药花锚石油醚提取物中的化学成分]

[Chemical Constituents in Petroleum Ether Extract of Mongolian Medicine Halenia corniculata].

作者信息

Tai Ba-da-la-hu, La Xi-na-mu-ji-la, Gui Rong, Bai Mei-rong, Bao Ming-lan, Ba Gen-na

出版信息

Zhong Yao Cai. 2015 Nov;38(11):2321-3.

PMID:27356384

Abstract

OBJECTIVE

To study the chemical constituents of Mongolian medicine Halenia corniculata.

METHODS

Positive phase and reversed phase silica gel, as well as Sephadex LH-20 methods were used to separate and purify. The structure of the isolated constituents was identified according to the NMR spectroscopy data and the literature data.

RESULTS

Nine compounds were isolated from 95% ethanol extracts of petroleum ether part of Halenia corniculata and identified as: 1-hydroxy-2,3,4,6-tetramethoxyxanthone (1), 1-hydroxy-2,3, 5-trimethoxyxanthone (2) 1-hydroxy-3,7-dimethoxyxanthone (3), 1-hydroxy-3,5,6,7,8-pentamethoxyxanthone (4), 1-hydroxy-2,3,4, 7-tetramethoxyxanthone (5), 1-hydroxy-3,5-dimethoxyxanthone (6),1-hydroxy-2,3,4,5,7-pentamethoxyxanthone (7), palmitic acid (8) and β-sitosterol (9).

CONCLUSION

Compounds 3, 4 and 8 are isolated from this genus for the first time, Compound 1 is isolated from this plant for the first time.

摘要

目的

研究蒙药花锚的化学成分。

方法

采用正相硅胶、反相硅胶以及葡聚糖凝胶LH - 20柱色谱法进行分离纯化。根据核磁共振波谱数据和文献资料鉴定分离得到成分的结构。

结果

从花锚石油醚部位的95%乙醇提取物中分离得到9个化合物，分别鉴定为：1 - 羟基 - 2,3,4,6 - 四甲氧基呫吨酮（1）、1 - 羟基 - 2,3,5 - 三甲氧基呫吨酮（2）、1 - 羟基 - 3,7 - 二甲氧基呫吨酮（3）、1 - 羟基 - 3,5,6,7,8 - 五甲氧基呫吨酮（4）、1 - 羟基 - 2,3,4,7 - 四甲氧基呫吨酮（5）、1 - 羟基 - 3,5 - 二甲氧基呫吨酮（6）、1 - 羟基 - 2,3,4,5,7 - 五甲氧基呫吨酮（7）、棕榈酸（8）和β - 谷甾醇（9）。