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低结核病病例发现率:一项基于加纳恩夸塔南区社区和卫生设施的促成因素研究

Low tuberculosis case detection: a community and health facility based study of contributory factors in the Nkwanta South district of Ghana.

作者信息

Amenuvegbe Gregory K, Francis Anto, Fred Binka

机构信息

School of Public Health, University of Health and Allied Sciences, Ho, Ghana.

School of Public Health, University of Ghana, Legon, Ghana.

出版信息

BMC Res Notes. 2016 Jun 29;9:330. doi: 10.1186/s13104-016-2136-x.

Abstract

BACKGROUND

Tuberculosis (TB) continues to pose a major public health problem globally. In Ghana, the national TB case detection rate is 81 %; however, some districts are not able to meet their case detection targets. This study was therefore carried out in the Nkwanta South district to identify possible factors contributing to low TB case detection.

METHODS

A cross sectional descriptive study involving the review of outpatients records for the year 2012 was conducted. Data on cough for 2 weeks or more duration, age, sex, area of residence and sputum smear examination were extracted. A community-based survey involving household contacts of TB patients and community based volunteers was also carried out. Data collected in the community included knowledge of TB status of relatives, level of socialization with TB patients and signs and symptoms of TB disease. Descriptive statistics including cross-tabulations were used to identify possible factors contributing to low TB case detection.

RESULTS

A total of 932 patients out of 3987 reported coughing for 2 weeks or more (23.4 %; 932/3987). Out of that, only 24.6 % (230/932) had sputum smear microscopy done, yielding 57 (24.8 %) positive cases. Five out of the 57 positive cases were found not registered for the initiation of treatment leading to a false primary default rate of 8.8 % per year. Eighty-five percent of the contacts were able to mention persistent cough as a sign/symptom of TB with 80.4 % indicating that TB can be cured. Only 10 % of health facilities provided diagnostic services in the district with only 25 % of staff having had training in TB management.

CONCLUSION

The study identified some factors (weak record review systems, inadequate diagnostic centres, lack of trained persons and some level of stigma at the community level) that could be contributing to low TB case detection in the Nkwanta South district.

摘要

背景

结核病在全球范围内仍然是一个重大的公共卫生问题。在加纳,全国结核病病例检出率为81%;然而,一些地区未能达到其病例检出目标。因此,本研究在南恩夸塔区开展,以确定导致结核病病例低检出率的可能因素。

方法

开展了一项横断面描述性研究,对2012年门诊记录进行回顾。提取了持续咳嗽2周或更长时间、年龄、性别、居住地区和痰涂片检查的数据。还开展了一项基于社区的调查,对象包括结核病患者的家庭接触者和社区志愿者。在社区收集的数据包括对亲属结核病状况的了解、与结核病患者的社交程度以及结核病的体征和症状。使用包括交叉表在内的描述性统计方法来确定导致结核病病例低检出率的可能因素。

结果

3987名患者中共有932名报告咳嗽持续2周或更长时间(23.4%;932/3987)。其中,只有24.6%(230/932)进行了痰涂片显微镜检查,检出57例(24.8%)阳性病例。57例阳性病例中有5例未登记开始治疗,导致每年的假初治失访率为8.8%。85% 的接触者能够提到持续咳嗽是结核病 的体征/症状之一,80.4% 的人表示结核病可以治愈。该地区只有10% 的医疗机构提供诊断服务,只有25% 的工作人员接受过结核病管理培训。

结论

该研究确定了一些可能导致南恩夸塔区结核病病例低检出率的因素(记录审查系统薄弱、诊断中心不足、缺乏经过培训的人员以及社区层面存在一定程度的污名化)

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d5a/4928284/696cb8703e7e/13104_2016_2136_Fig1_HTML.jpg

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