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日本高效抗逆转录病毒治疗覆盖率及病毒抑制率情况:下游人类免疫缺陷病毒护理谱的出色表现

The Prevalence of High Antiretroviral Coverage and Viral Suppression in Japan: an Excellent Profile for a Downstream Human Immunodeficiency Virus Care Spectrum.

作者信息

Miyazaki Naoko, Sugiura Wataru, Gatanaga Hiroyuki, Watanabe Dai, Yamamoto Yasuyuki, Yokomaku Yoshiyuki, Yoshimura Kazuhisa, Matsushita Shuzo

机构信息

The Institute of Medical Science, The University of Tokyo.

出版信息

Jpn J Infect Dis. 2017 Mar 24;70(2):158-160. doi: 10.7883/yoken.JJID.2015.599. Epub 2016 Jun 30.

Abstract

We investigated the effectiveness of the Japanese health care system for human immunodeficiency virus/acquired immunodeficiency virus (HIV/AIDS), in terms of prevention, diagnosis, access to antiretroviral treatment, and treatment outcomes. Clinical information on HIV/AIDS cases was collected via questionnaires sent to 377 registered HIV/AIDS clinics in Japan. Data on 9,040 and 14,569 cases were collected in 2009 and 2014, respectively. The percentages of cases undergoing treatment were 69.6% and 87.8% in 2009 and 2014, respectively, demonstrating an improvement in treatment coverage over the 5 years between the 2 surveys. The proportion of cases with undetectable HIV RNA in the 2014 survey was 87.7%. Thus, our survey revealed that the 2 of the United Nations AIDS Fast-Track targets, 90% treated and 90% virally suppressed, are close to being achieved. However, Japan appears to have fallen short of the upstream target of 90% diagnosed. Japan needs to radically reform its strategies for encouraging people to undergo HIV testing and to develop a system for estimating the number of people living with HIV.

摘要

我们从预防、诊断、获得抗逆转录病毒治疗以及治疗结果等方面,调查了日本医疗保健系统针对人类免疫缺陷病毒/获得性免疫缺陷综合征(HIV/AIDS)的有效性。通过向日本377家注册的HIV/AIDS诊所发送问卷,收集了HIV/AIDS病例的临床信息。2009年和2014年分别收集了9040例和14569例的数据。2009年和2014年接受治疗的病例百分比分别为69.6%和87.8%,表明在这两次调查间隔的5年中,治疗覆盖率有所提高。在2014年的调查中,HIV RNA检测不到的病例比例为87.7%。因此,我们的调查显示,联合国艾滋病快速通道的两个目标,即90%的患者接受治疗和90%的患者病毒得到抑制,已接近实现。然而,日本似乎未达到90%的患者得到诊断这一上游目标。日本需要从根本上改革其鼓励人们接受HIV检测的策略,并建立一个估计HIV感染者人数的系统。

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